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SODIUM ZINC HISTIDINE DITHIOOCTANAMIDE.

Valuable CAS - / ANTIOXIDANT

SODIUM ZINC HISTIDINE DITHIOOCTANAMIDE is a novel complex designed to deliver targeted benefits, primarily functioning as an antioxidant to mitigate oxidative stress on the skin. This ingredient also exhibits promising antibacterial properties, making it a potential candidate for addressing acne-prone skin concerns.

Summary

Antioxidant Antibacterial

Science

Mechanism of Action

This complex operates by leveraging the multifaceted biological roles of zinc, an essential element. Zinc acts as a crucial cofactor in numerous enzymatic processes vital for skin health, including DNA synthesis and cell division. It also directly contributes to antioxidant defense by protecting against free radical damage and supporting immune functions. Histidine, an essential amino acid, enhances zinc's bioavailability and acts as a chelating agent, potentially amplifying the complex's overall efficacy.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Unknown
Optimal pH N/A
0 7 14

Stability

Related zinc(II) complexes with histidine have demonstrated good physicochemical stability in preparations.

Synergies

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Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) has not specifically evaluated SODIUM ZINC HISTIDINE DITHIOOCTANAMIDE, though various zinc salts have been deemed safe in cosmetics when formulated to prevent irritation. The Scientific Committee for Consumer Safety (SCCS) has approved this substance for use in cosmetic products, although its application may be subject to specific restrictive conditions, which could include purity criteria, maximum concentration limits, or restrictions to particular product categories as per Annex III of the EC Cosmetics Regulation. Patch tests on 25 healthy volunteers showed no irritation or allergy, indicating a low sensitization risk for the related complexes.

Your Skin

Skin Compatibility

No Normal
No Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

SODIUM ZINC HISTIDINE DITHIOOCTANAMIDE offers valuable antioxidant benefits and demonstrates significant potential for acne management due to its antibacterial activity and low irritation risk, though specific clinical concentration data for this exact ingredient is limited.

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