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SODIUM STEAROYL CHONDROITIN SULFATE.

Valuable CAS 222400-50-2 / HAIR CONDITIONING, SKIN CONDITIONING

Sodium Stearoyl Chondroitin Sulfate is a potent glycosaminoglycan (GAG) derived from chondroitin sulfate, recognized for its exceptional water-binding capabilities. As a component of the skin's extracellular matrix, it forms a hydrating film, delivering immediate and profound moisturizing benefits to maintain skin health and vitality.

Summary

Humectant Skin conditioning Anti-inflammatory Anti-aging Skin firming Wound healing support Antistatic Hair conditioning

Science

Mechanism of Action

This ingredient functions as a powerful humectant, effectively attracting and retaining moisture within the skin. It exhibits a high affinity for the skin's surface, establishing a water-rich protective film that provides both immediate and sustained hydration. Beyond its humectant role, it supports the skin's structural integrity by replenishing aged mucopolysaccharides and fostering their regeneration. Furthermore, it demonstrates anti-inflammatory properties and may contribute to skin firming, wrinkle reduction, and overall anti-aging effects through mechanisms such as blocking matrix metalloproteinases (MMPs) and promoting collagen synthesis and cell movement for wound healing.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH 5.5 – 7.5
0 7 14

Stability

Freely soluble in water, this ingredient demonstrates remarkable stability under neutral conditions at lower temperatures. Degradation, leading to lower-molecular-mass fragments and desulfated products, commences around 60 degrees Celsius after prolonged exposure (500-600 hours). Under basic conditions, a decrease in molecular mass can be observed due to beta-elimination. A 1% solution maintains a pH between 5.5 and 7.5. Long-term stability studies indicate it retains its profile for at least 36 months when stored at standard conditions (25 ± 2 °C and 60 ± 5 % relative humidity).

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) has not specifically evaluated Sodium Stearoyl Chondroitin Sulfate. However, its parent compound, Chondroitin Sulfate Sodium, is recognized as Generally Recognized As Safe (GRAS) by the FDA for oral consumption in conventional foods up to 200 mg per serving, with a maximum daily intake of 1200 mg. For topical skincare, Sodium Chondroitin Sulfate is generally considered safe with no known side effects, though individuals with sensitive skin are advised to perform a patch test.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Sodium Stearoyl Chondroitin Sulfate is a valuable humectant and GAG that significantly boosts skin hydration and supports overall skin health, exhibiting broad compatibility and a favorable safety profile.

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