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SODIUM PALMITOYL SARCOSINATE.

Valuable CAS 4028-10-8 / CLEANSING, HAIR CONDITIONING, SURFACTANT - CLEANSING

Sodium Palmitoyl Sarcosinate is a mild, amino acid-derived surfactant recognized for its dual functionality as a gentle cleansing agent and effective skin and hair conditioner. It helps emulsify formulations while respecting the skin's natural barrier.

Surfactant Cleansing Agent Hair Conditioning Agent Skin Conditioning Agent Emulsifier

Science

Operating as a sophisticated surfactant, Sodium Palmitoyl Sarcosinate proficiently lowers surface tension, enabling the harmonious blending of typically immiscible oil and water phases. This action facilitates the effective attraction and removal of dirt, excess oil, and other impurities from both skin and hair, ensuring thorough yet gentle cleansing without compromising barrier integrity. Additionally, it contributes to skin conditioning, enhances hair's body, suppleness, and sheen, and acts as an emulsifier to stabilize product formulations. Notably, related sarcosinates have shown potential to boost the dermal penetration of co-formulated active ingredients.


Research

Low confidence
Effective range 0.081–5%
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH 5 – 9
0 7 14

Stability

Sarcosinate salts exhibit superior water solubility and reduced susceptibility to water hardness compared to conventional soaps. Stability is maintained across a pH range of 5 to 9, with thermal stability up to 100°C. For optimal formulation integrity, a pH generally exceeding 6 is recommended. It demonstrates excellent compatibility with various glycols, silicones, solvents, and phosphate esters.

Synergies

  • Glycols
  • Silicones
  • Solvents
  • Phosphate esters
  • Ingredients benefiting from enhanced dermal penetration

Conflicts

  • Ingredients or environmental conditions that may facilitate the formation of N-nitroso compounds.
  • Ingredients whose safety profiles are predicated on minimal dermal absorption, due to its potential to enhance penetration.

Safety

CIR Status
Safe with restrictions
Max tested
5%
Sensitization risk Low

The CIR Expert Panel considers Sodium Palmitoyl Sarcosinate safe for cosmetic use when expertly formulated to be non-irritating. It is approved for use in rinse-off products and safely utilized in leave-on formulations at concentrations up to 5%. A critical restriction is its avoidance in products where N-nitroso compounds could potentially form, as its precursor, sarcosine, can generate N-nitrososarcosine, a known animal carcinogen. Related sarcosinates have received FDA approval for indirect food additive use, and EWG rates common safety concerns for Sodium Palmitoyl Sarcosinate as 'LOW'.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Valuable

Sodium Palmitoyl Sarcosinate is a valuable, gentle multi-functional ingredient offering effective cleansing and conditioning, supported by a well-defined safety profile and broad formulation compatibility, provided N-nitroso compound formation is prevented.


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