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SODIUM OCTOXYNOL-9 SULFATE.

Valuable CAS 12627-38-2 / CLEANSING, SURFACTANT - CLEANSING, SURFACTANT - EMULSIFYING

Sodium Octoxynol-9 Sulfate is a highly functional surfactant, integral for its capacity to emulsify, cleanse, and solubilize. It proficiently reduces surface tension, enabling the harmonious blend of dissimilar substances like oil and water, making it effective for rinsing away impurities and stabilizing complex formulations.

Summary

Surfactant Emulsifying Cleansing Solubilizing

Science

Mechanism of Action

This ingredient functions as a surfactant by reducing the surface tension between different substances. This property allows it to effectively form and stabilize emulsions, ensuring a uniform mixture of ingredients that would otherwise separate. Furthermore, its cleansing action involves enabling water to encapsulate and rinse away oil and dirt from skin and hair. As a longer-chain octoxynol, it also exhibits solubilizing capabilities, assisting in the dissolution of other compounds within a solvent.

Research

Clinical Evidence

High confidence
Effective range 1–2%
Optimal

1%

Key findings

  1. 01 In a 4-day clinical patch test involving nine subjects, Octoxynol-9 demonstrated non-irritant properties at a 1.0% concentration.
  2. 02 At a 2.0% concentration, formulations containing Octoxynol-9 were classified as ranging from minimally to moderately irritating in a 24-hour single-insult, occlusive patch test in humans.
  3. 03 Extensive studies involving up to 206 subjects consistently observed no skin sensitization reactions to Octoxynol-9 across concentrations of 0.1%, 0.5%, and 8.0%.

Transparency

Dusting Analysis

Not commonly dusted

Sodium Octoxynol-9 Sulfate is a functional surfactant, not an active ingredient typically associated with 'dusting' due to specific efficacy or irritation thresholds.

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Octoxynol-9 is generally stable. However, storing material with free ethylene oxide exceeding 100 ppm in a closed container may pose an explosion hazard due to gas release.

Conflicts

  • strong oxidizing agents

Safety

Safety Profile

CIR Status
Safe as used
Max tested
2%
Sensitization risk Low

The CIR Expert Panel affirms the safety of Sodium Octoxynol-9 Sulfate for use in both rinse-off and leave-on cosmetic products, recommending limits on trace impurities such as 1,4-dioxane, ethylene oxide, or unreacted C9 phenols. Its classification as a long-chain octoxynol mitigates ocular irritancy concerns associated with shorter-chain octoxynols. The maximum reported use concentration in skin cleansing preparations is 2% (2022 data), and up to 5% in cologne and toilet water (2001 data).

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Sodium Octoxynol-9 Sulfate is a valuable functional ingredient, widely accepted as safe for its critical surfactant properties, effectively aiding in cleansing and stabilizing cosmetic formulations with a low risk of sensitization.

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