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Moumoujus

SODIUM METHYLESCULETIN ACETATE.

Valuable CAS 95873-69-1 / ORAL CARE

Sodium Methylesculetin Acetate is a multi-functional active ingredient engineered to address a spectrum of skin concerns. It visibly brightens complexion, diminishes hyperpigmentation, and offers comprehensive anti-aging benefits by combating oxidative stress and promoting collagen health. Additionally, it provides soothing relief for sensitive skin and augments UV protection.

Summary

Antioxidant Skin-brightening Anti-aging Soothing UV Protective

Science

Mechanism of Action

This compound operates by inhibiting the tyrosinase enzyme, thereby reducing melanin synthesis for a visibly brighter and more even skin tone. It acts as a potent antioxidant, neutralizing free radicals to guard against environmental damage and premature aging. Furthermore, it modulates pro-inflammatory molecules, contributing to skin soothing, while simultaneously supporting collagen synthesis and preventing its degradation to improve firmness and reduce fine lines. An additional benefit includes its capacity to absorb UV radiation, offering an enhanced layer of defense when paired with sunscreens.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH 6 – 8
0 7 14

Stability

Sodium Methylesculetin Acetate exhibits exceptional aqueous solubility, dissolving at concentrations exceeding 1,000,000 mg/L in pure water at ambient temperature. It maintains robust solubility within a neutral pH range of 6.0 to 8.0, with its acetate component providing buffering capacity. Solubility significantly diminishes below pH 4, with potential precipitation of the free acid form occurring below pH 2, necessitating precise pH control in acidic formulations. It demonstrates limited solubility in moderately polar solvents and negligible solubility in nonpolar solvents, and its amorphous nature supports versatile integration into various matrices.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

The ingredient is generally considered to have a low hazard profile, with 100% of company reports to the ECHA C&L Inventory indicating it does not meet GHS hazard criteria. EWG's Skin Deep database further classifies it as 'LOW' risk across concerns including cancer, allergies, immunotoxicity, and developmental/reproductive toxicity, suggesting minimal risk of irritation.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

Sodium Methylesculetin Acetate is a valuable multi-faceted ingredient offering significant benefits in skin brightening, anti-aging, soothing, and environmental protection with a favorable safety profile.

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