Science
Mechanism of Action
This amphiphilic, anionic surfactant operates via its unique molecular structure, featuring a 12-carbon hydrophobic chain and a hydrophilic carboxylate group. It efficiently cleanses by facilitating the mixing of water with oils and dirt, enabling their easy removal. Its mild degreasing properties support skin hydration, while it enhances lather in cleansing formulations and can mitigate potential irritation from other surfactants. Furthermore, it aids in moisture retention by forming a hydrophobic protective layer on the epidermal surface, and exhibits antimicrobial activity, inhibiting bacterial flora at 0.25% and demonstrating fungistatic properties at 1% in aqueous dispersions.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 Clinical studies demonstrate that Sodium Lauroyl Sarcosinate at concentrations between 2-5% is non-irritating and non-sensitizing to human skin.
- 02 In a facial cleanser, it was observed to decrease porphyrin levels, alter the skin lipidome by increasing phosphatidylglycerol and phosphatidylcholine while reducing ceramides, and significantly reduce the alpha diversity of the prokaryotic microbial community. However, it did not extensively influence other skin biophysical parameters.
- 03 Specific antimicrobial effects are noted, with inhibition of bacterial flora at 0.25% and fungistatic action at 1% in aqueous dispersions.
Transparency
Dusting Analysis
Sodium Lauroyl Sarcosinate is a foundational anionic surfactant primarily utilized for its cleansing, foaming, and emulsifying properties. Its core functional role in formulations necessitates its inclusion at effective concentrations, making it an unlikely candidate for 'dusting' or minimal inclusion for marketing purposes.
The Formula
Formulation
Stability
Highly water-soluble (293 g/L) and stable across a broad pH range from slightly acidic (5.5) to moderately alkaline (up to 8.5 and beyond). It exhibits excellent chemical stability and is compatible with various glycols, silicones, solvents, and phosphate esters. Its foaming and detergent properties are maintained even with substantial amounts of emollients, and it demonstrates good resistance to hard water.
Synergies
- Glycols
- Silicones
- Solvents
- Phosphate esters
- Emollients
- Other surfactants (by reducing their potential irritation)
Conflicts
- Strong oxidizing agents
- Ingredients that could form N-nitroso compounds
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel concluded that Sodium Lauroyl Sarcosinate is safe for use in rinse-off products up to 15% and in leave-on products at concentrations up to 5%. It is generally considered non-irritating and non-sensitizing, confirmed by clinical studies at 2-5%. A significant safety consideration is the potential for nitrosamine formation if used in conjunction with ingredients that can create N-nitroso compounds. Reputable manufacturers implement rigorous testing protocols to ensure undetectable levels of nitrosamines and formulate products to prevent their formation.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Sodium Lauroyl Sarcosinate is a valuable, mild anionic surfactant offering effective cleansing, foaming, and emulsifying properties with proven low irritancy and broad compatibility across all skin types.
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References
Sources