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SODIUM HYDROXYPROPYL CYCLODEXTRIN OCTENYLSUCCINATE.

Insufficient Data / DEODORANT, EMULSION STABILISING, HUMECTANT, SURFACTANT - CLEANSING

Sodium Hydroxypropyl Cyclodextrin Octenylsuccinate is a sophisticated cyclodextrin derivative engineered to encapsulate active ingredients, significantly enhancing their stability, solubility, and controlled delivery within skincare formulations. This multifunctional ingredient also acts as a humectant, surfactant, and emulsion stabilizer, while effectively minimizing body odors.

Encapsulation Stabilizer Solubility Enhancer Bioavailability Enhancer Controlled Release Agent Humectant Surfactant Odor Reducer Emulsion Stabilizer

Science

This chemically modified cyclodextrin possesses a unique structure with a hydrophilic exterior and a lipophilic internal cavity, enabling it to form inclusion complexes with hydrophobic molecules. This encapsulation protects active ingredients from degradation by light and and heat, boosts their water solubility, and optimizes their bioavailability and sustained release on the skin. Beyond its encapsulation prowess, it functions as a humectant, attracting and retaining moisture, and serves as a surfactant for gentle cleansing. It also stabilizes emulsions and helps mitigate undesirable body odors.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH 3 – 9
0 7 14

Stability

This ingredient exhibits excellent stability in solution across a broad pH range of 3.0 to 9.0, maintaining integrity under stress conditions such as elevated temperature (40°C) and high oxygen pressure.

Conflicts

  • Polysorbate 80 (PS80)
  • Polysorbate 20 (PS20)

Safety

CIR Status
Insufficient data
Sensitization risk Unknown

The Cosmetic Ingredient Review (CIR) Expert Panel noted 'insufficient data' for Sodium Hydroxypropyl Cyclodextrin Octenylsuccinate itself, despite proposing its inclusion in a broader assessment of related ingredients in 2018. While a specific 'safe as used' conclusion or maximum concentration has not been established for this ingredient, other cyclodextrins like native cyclodextrins, 2-hydroxypropyl-β-cyclodextrin, and hydroxyethyl-β-cyclodextrin are endorsed as safe by the CIR. Furthermore, the Scientific Committee on Consumer Safety (SCCS) in the EU classifies cyclodextrins as excipients, and the FDA recognizes native cyclodextrins as generally safe (GRAS) for food use.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Insufficient Data

While offering significant benefits in ingredient stabilization, solubility, and hydration across all skin types, comprehensive safety data for Sodium Hydroxypropyl Cyclodextrin Octenylsuccinate itself is currently insufficient according to the CIR Expert Panel.


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