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Moumoujus

SODIUM HYDROLYZED CASEIN.

Valuable CAS 222400-26-2 / HAIR CONDITIONING, SKIN CONDITIONING

Sodium Hydrolyzed Casein is a hydrolyzed milk protein providing amino acids and peptides that support skin hydration and barrier function. It demonstrates an anti-glycation mechanism, which may contribute to reducing facial pigmentation.

Summary

Skin Conditioning Antistatic Hair Conditioning Hydration Support Barrier Support Anti-glycation

Science

Mechanism of Action

This ingredient functions as a skin conditioning and antistatic agent. As a hydrolyzed protein, it delivers essential amino acids and peptides to the skin, enhancing hydration and supporting the skin's natural barrier. Research suggests an anti-glycation mechanism, where it can decrease skin accumulation of Advanced Glycation End Products (AGEs), thereby potentially reducing facial pigmentation. Its amphiphilic nature also aids in ingredient interaction and potential delivery.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Commonly dusted

While mechanistic data supports anti-glycation and a clinical study shows pigmentation reduction, this evidence is derived from oral intake of casein hydrolysate, not direct topical application of Sodium Hydrolyzed Casein. Therefore, specific topical efficacy data for anti-pigmentation at a defined concentration is currently lacking.

The Formula

Formulation

Solubility
Water
Optimal pH 7 – 8
0 7 14

Stability

Hydrolyzed sodium caseinates exhibit high solubility (>90%) across a broad pH range of 2 to 8. Optimal stability and maximal solubility are observed in neutral to alkaline pH ranges, with peak solubility around pH 7.0.

Safety

Safety Profile

CIR Status
Safe as used
Max tested
30%
Sensitization risk Low

The CIR Expert Panel concluded that Sodium Hydrolyzed Casein and related bovine milk proteins are safe in cosmetic practices. While bovine milk proteins are known food allergens, the CIR Panel determined that immediate hypersensitivity reactions from cosmetic use are not likely. Safety tests for Hydrolyzed Casein showed negative results for irritation and sensitization up to 30%. Individuals with known casein allergies should avoid this ingredient. The FDA generally recognizes bovine milk proteins as safe (GRAS).

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Sodium Hydrolyzed Casein is a valuable skin conditioning agent with an excellent safety profile, offering hydration and barrier support, and showing promising anti-glycation effects, though direct topical clinical efficacy for pigmentation reduction warrants further research.

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