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SODIUM GRAPESEEDAMIDOPROPYL PG-DIMONIUM CHLORIDE PHOSPHATE.

Valuable / HAIR CONDITIONING, SKIN CONDITIONING, SURFACTANT - CLEANSING

This naturally derived triglyceride phospholipid expertly mimics the body's own phospholipids, delivering essential fatty acids to the skin. Sourced from grapeseed oil, it provides powerful antioxidant protection while also offering broad-spectrum antimicrobial activity.

Antioxidant Hair Conditioning Skin Conditioning Surfactant Antimicrobial

Science

As a naturally derived triglyceride phospholipid, this ingredient functions by emulating endogenous phospholipids, adhering effectively to both skin and hair surfaces. It actively deposits essential fatty acids, contributing to skin nourishment and repair. Its origin in grapeseed oil bestows potent antioxidant capabilities via flavonoid oligomeric procyanidins, concurrently demonstrating broad-spectrum antimicrobial action and mitigating irritation induced by anionic compounds.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH 5 – 5.5
0 7 14

Stability

The raw material typically presents a pH of 7.5 (10% IPA/H2O). However, for optimal performance and skin compatibility within the final product, adjusting the pH to a range of 5.0 to 5.5, commonly with citric acid, is recommended. It is inherently water-soluble or dispersible, simplifying integration into aqueous formulations. Gentle heating to 40-50°C may be necessary to achieve clarity in some formulations. When combining ingredients, high-shear mixing is suggested, with care to avoid air introduction.

Conflicts

  • Polymeric anionic rheology modifiers (anionic thickening agents) may be incompatible if not properly compatibilized, potentially resulting in precipitation or significant viscosity reduction.

Safety

CIR Status
Not reviewed
Sensitization risk Low

Extensive safety assessments indicate a low risk of irritation and sensitization. Acute skin irritation tests (48-hour occlusive patch test on 53 human subjects) demonstrated no visible skin reaction. Eye irritation tests (MatTek Epi-Ocular) classified it as 'non-irritating'. Repeat Insult Patch Testing (HRIPT) confirmed no potential for dermal irritation or allergic contact sensitization. While this specific ingredient lacks a direct CIR review, a related compound, Cocamidopropyl PG-Dimonium Chloride Phosphate, is deemed safe for cosmetic use with specified limitations. EWG Skin Deep rates this ingredient with low overall concerns.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Valuable

A highly versatile and well-tolerated ingredient that provides comprehensive conditioning, antioxidant protection, and antimicrobial benefits to both skin and hair across a broad range of product types.


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