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Moumoujus

SODIUM GLUCOSE-6 PHOSPHATE.

Avoid CAS 54010-71-8 / SKIN CONDITIONING

Sodium Glucose-6 Phosphate (G6P) is a foundational molecule in cellular energy metabolism, serving as a critical intermediate in pathways vital for cellular function. It plays a role in generating antioxidant defenses and synthesizing components essential for cellular regeneration.

Summary

Skin Conditioning Antioxidant Support

Science

Mechanism of Action

As a key intermediate in cellular metabolic pathways, including glycolysis and the pentose phosphate pathway, Sodium Glucose-6 Phosphate is central to cellular energy dynamics. Its involvement in the pentose phosphate pathway specifically leads to the production of NADPH, a crucial coenzyme that supports cellular redox balance and provides robust antioxidant defense. Furthermore, it contributes to the synthesis of ribonucleotides, which are fundamental building blocks for nucleic acids and thus essential for cellular repair and renewal. In a skincare context, this biological role suggests potential to support optimal cellular function, bolster antioxidant capacity, and promote skin regeneration.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

No information suggests this ingredient is commonly 'dusted' in cosmetic formulations.

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

While the D-Glucose 6-phosphate sodium salt in powder form exhibits high stability, remaining non-hygroscopic at room temperature, its stability is significantly reduced in aqueous solutions. These solutions are generally recommended for use within one day of preparation.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

Sodium Glucose-6 Phosphate has not been reviewed by the Cosmetic Ingredient Review (CIR) or the SCCS. Its mentioned FDA status pertains solely to its use as a reagent in diagnostic devices, not as a cosmetic ingredient. Research chemical suppliers explicitly label this compound for 'research use only,' advising against its application as a drug, medical device, food additive, cosmetic, or household chemical. Safety Data Sheets (SDS) further warn that the substance 'May be harmful in contact with skin' and recommend thorough washing after handling, indicating potential skin irritation or harm.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Avoid

Given the complete absence of cosmetic safety review, explicit warnings from research chemical suppliers against its use in cosmetic products, and potential for harm upon skin contact, Sodium Glucose-6 Phosphate is not deemed suitable for skincare formulations.

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