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SODIUM CARBOXYMETHYL EUGLENA GRACILIS EXTRACT.

Valuable CAS - / SKIN CONDITIONING

Derived from the microalga Euglena gracilis, this ingredient is a potent skin conditioner and humectant. It is designed to enhance skin vitality, improve elasticity, and provide robust antioxidant and anti-inflammatory benefits, contributing to a more resilient and youthful complexion.

Summary

moisturizer/humectant antioxidant skin conditioning anti-aging firming elasticity-improving revitalizing

Science

Mechanism of Action

SODIUM CARBOXYMETHYL EUGLENA GRACILIS EXTRACT operates by delivering a rich blend of active compounds including paramylon (a β-1,3-glucan), essential vitamins like E, carotenoids, and polyunsaturated fatty acids. This synergy enhances the skin's barrier function, boosts hydration, and mitigates oxidative stress. In vitro studies demonstrate its capacity to stimulate collagen and elastin production, crucial for maintaining skin firmness and elasticity. The ingredient also exhibits significant anti-inflammatory actions and supports cellular energy metabolism through phosphoinositide production, promoting cell renewal and revitalizing skin.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

3%

Key findings

  1. 01 Observed increased cutaneous vitality and reduced skin deformability after 14 days of topical treatment, indicating improved skin health and resilience.
  2. 02 Euglena gracilis extracts effectively reduced the production of pro-inflammatory mediators, such as TNF-α and nitrite, in human macrophages and microglial cultures, suggesting potent anti-inflammatory properties.
  3. 03 An aqueous Euglena gracilis extract, when incorporated into a hydrogel, accelerated wound healing in mice by promoting re-epithelization and decreasing excessive fibroplasia without inducing significant inflammation.

Transparency

Dusting Analysis

Not commonly dusted

No data available to suggest common dusting practices or red flag percentages for this ingredient. The optimal percentage from clinical data (3%) supports its active role.

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Carboxymethylation significantly enhances the water solubility of paramylon, a key component of Euglena gracilis. While specific pH stability for the extract isn't detailed, the organism itself thrives in a pH range of 3.5-7.5, with an optimal range between 3 and 6, which may inform formulation stability considerations.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel has not specifically evaluated SODIUM CARBOXYMETHYL EUGLENA GRACILIS EXTRACT. However, the European Food Safety Authority (EFSA) assigned a Qualified Presumption of Safety (QPS) status to dried whole cell Euglena gracilis for use as a novel food, with no adverse effects noted in subchronic toxicity studies up to 3,300 mg/kg body weight. In vitro studies confirm non-cytotoxic concentrations up to 100 µg/mL.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

SODIUM CARBOXYMETHYL EUGLENA GRACILIS EXTRACT is a valuable multi-functional ingredient that enhances skin vitality, hydration, and elasticity while offering antioxidant and anti-inflammatory benefits across all skin types.

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