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SODIUM ARACHIDATE.

Valuable / BUFFERING, EMULSION STABILISING, SURFACTANT - CLEANSING, SURFACTANT - EMULSIFYING, VISCOSITY CONTROLLING

Sodium Arachidate is the monosodium salt of arachidic acid, a saturated fatty acid. In skincare formulations, it serves as a multifunctional additive, providing surfactant, emulsifying, and stabilizing properties, while also demonstrating a potential role in modulating skin inflammation.

Summary

Modulator of inflammation Surfactant Emulsifying agent Emulsion stabilizer pH regulator Viscosity control agent

Science

Mechanism of Action

This saturated fatty acid salt has been observed to modulate the expression of cyclooxygenase-2 (COX-2), an enzyme pivotal for inflammatory processes and tissue repair within the skin. Beyond this potential biological interaction, Sodium Arachidate functions as a crucial cosmetic additive, acting as a surfactant, an emulsifying agent, an emulsion stabilizer, a pH regulator, and a viscosity control agent, thereby enhancing product texture and stability.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 An in vitro study demonstrated that Sodium Arachidate, at a concentration of 5 µM, effectively inhibited rabbit neutrophil aggregation induced by N-formyl-methionyl-leucyl-phenylalanine (fMLP). This suggests a potential role in mitigating inflammatory responses at a cellular level.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Stability

As a salt of a saturated fatty acid, Sodium Arachidate is generally more stable than salts of unsaturated fatty acids, which are highly susceptible to oxidation. While specific stability data is not extensively detailed, general considerations for fatty acid salts suggest that purging solutions with an inert gas can prolong their shelf life.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

Sodium Arachidate itself has not been reviewed by the Cosmetic Ingredient Review (CIR). However, its parent compound, Arachidic Acid, is considered by Australia's NICNAS to pose no unreasonable risk to public health. The EPA Safer Choice program classifies Sodium Arachidate as a chemical of low concern based on experimental and modeled data. EWG Skin Deep also rates it as 'Low Concern' for cancer, allergies & immunotoxicity, and developmental & reproductive toxicity.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Sodium Arachidate is a valuable ingredient, prized for its versatile functional roles in formulation chemistry and its potential to modulate inflammatory responses in the skin, all while maintaining a low overall safety concern profile.

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