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Moumoujus

SIMMONDSIA CHINENSIS LEAF EXTRACT.

Valuable CAS 90045-98-0 / HUMECTANT

Simmondsia Chinensis Leaf Extract, derived from the jojoba plant, is a multifaceted botanical ingredient known for enhancing skin health. It actively supports the skin's structural integrity and barrier function, while simultaneously delivering hydration and soothing properties.

Summary

humectant skin barrier repair anti-inflammatory antioxidant firming antimicrobial

Science

Mechanism of Action

This extract operates by upregulating the genetic expression of key components involved in epidermal barrier repair and cellular cohesion. This process leads to improvements in skin structure, increased firmness, and enhanced moisture retention by mitigating transepidermal water loss (TEWL). Furthermore, its rich flavonoid profile contributes antioxidant, anti-inflammatory, and antimicrobial benefits by attenuating lipoxygenase activity, a critical enzyme in inflammatory pathways.

Research

Clinical Evidence

Medium confidence
Effective range ≥3%
Optimal

3%

Key findings

  1. 01 A clinical study demonstrated that topical application of a 3% concentration in a cosmetic cream yielded a tensor effect, reduced transepidermal water loss (TEWL) and desquamation, and improved overall skin structure, strength, firmness, cohesion, and barrier function by enhancing gene expression related to barrier repair and skin cell cohesion.
  2. 02 Jojoba leaf extract flavonoids have shown potential to attenuate lipoxygenase activity, indicating anti-inflammatory properties.
  3. 03 Methanolic extracts from Simmondsia chinensis exhibited wound healing and antimicrobial activities against Staphylococcus aureus and Escherichia coli in experimental models.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel has not specifically reviewed 'Simmondsia Chinensis Leaf Extract.' However, related Jojoba seed-derived ingredients have been deemed safe. EWG Skin Deep assesses 'SIMMONDSIA CHINENSIS (JOJOBA) LEAF EXTRACT' with low concerns regarding cancer, allergies, immunotoxicity, developmental and reproductive toxicity, and usage restrictions.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
No Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Simmondsia Chinensis Leaf Extract is a valuable ingredient for improving skin barrier function, enhancing firmness, providing hydration, and offering soothing benefits across multiple skin types.

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