Science
Mechanism of Action
This single-chain recombinant human peptide is synthesized to be structurally identical to the human gene responsible for coding Collagen Alpha 1, a fundamental component of dermal integrity. Its primary function involves drawing and binding moisture, thereby enhancing skin hydration as a humectant. Furthermore, as a signaling peptide, it is understood to activate the body's endogenous skin repair processes, stimulating cellular regeneration and reinforcing the overall skin structure. This comprehensive action is postulated to contribute to a visible reduction in the appearance of wrinkles and a strengthened skin barrier.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Safety
Safety Profile
While the Cosmetic Ingredient Review (CIR) Expert Panel has evaluated natural silk protein derivatives, SILKWORM RH-POLYPEPTIDE-47 (also known as SILKWORM SH-POLYPEPTIDE-47) is a recombinant human peptide, and a direct safety assessment by CIR or SCCS specifically for this ingredient was not identified in the available research. Its safety profile for cosmetic use requires further dedicated assessment.
Your Skin
Skin Compatibility
Our Assessment
Verdict
SILKWORM RH-POLYPEPTIDE-47 exhibits a compelling mechanism for enhancing skin hydration and structure; however, definitive clinical efficacy data and a formal safety review are currently not available, warranting further research for a conclusive assessment.
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References
Sources