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SIDERITIS SYRIACA EXTRACT.

Valuable / ANTIOXIDANT, SKIN CONDITIONING, SKIN PROTECTING

Sideritis Syriaca Extract is a botanical ingredient rich in polyphenols and flavonoids, primarily recognized for its potent antioxidant and anti-inflammatory capabilities. It also functions as a skin conditioning and protecting agent, suitable for a broad range of skin types.

Summary

antioxidant anti-inflammatory skin conditioning skin protecting anti-aging (potential) antimicrobial (potential)

Science

Mechanism of Action

This extract exerts its primary effects through a high concentration of polyphenols and flavonoids, acting as a powerful antioxidant and anti-inflammatory agent. It helps neutralize free radicals via naturally occurring non-enzymatic antioxidants and may enhance endogenous antioxidant enzyme activity. Research on related Sideritis species suggests potential anti-aging benefits, including inhibiting bacterial collagenase activity, reducing advanced glycation end product (AGE) formation, and mitigating ultraviolet B (UVB)-induced matrix metalloproteinase-1 (MMP-1) expression. Additionally, certain Sideritis species exhibit antimicrobial properties.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

No data suggests Sideritis Syriaca Extract is commonly 'dusted' or used at ineffective concentrations in formulations.

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Stability

The extract contains a diverse range of phytochemicals, including water-soluble flavonoid glycosides and phenolic acids, as well as less polar flavonoid aglycones soluble in organic solvents. Optimal extraction often utilizes water-ethanol mixtures (e.g., 20/80 ratio) to recover a broad spectrum of bioactive compounds.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

The Cosmetic Ingredient Review (CIR) Expert Panel has not specifically evaluated SIDERITIS SYRIACA EXTRACT. However, the European Medicines Agency (EMA) recognizes Sideritis syriaca L. (as 'Sideritis herba') for traditional oral use, with no reported side effects for conditions like coughs or mild gastrointestinal discomfort. Safety data from a related species, Sideritis scardica, indicated no acute or repeated-dose oral toxicity in rats (up to 1000 mg/kg bw of a 20% v/v ethanol extract) and was non-mutagenic, generally supporting a favorable safety profile for the genus.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Sideritis Syriaca Extract is a valuable botanical ingredient offering significant antioxidant and anti-inflammatory benefits, with promising preliminary data for anti-aging and antimicrobial properties, making it suitable for a wide range of precision skincare applications.

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