Science
Mechanism of Action
Operating through diverse biochemical pathways, Shorea Robusta Resin extract contributes to improved skin appearance and tactile sensation by restoring essential moisture, refining texture, and promoting epidermal softness and suppleness. Its pronounced wound-healing efficacy is mediated by accelerated wound contraction, alongside an increase in hydroxyproline content and tensile strength. Additionally, it confers cellular protection via an oxidative defense mechanism, mitigates oxidative stress, and exhibits proven anti-inflammatory, antimicrobial (effective against both bacterial and fungal pathogens), and astringent actions on the skin.
Research
Clinical Evidence
Medium confidence30%
Key findings
- 01 In an excision wound model in rats, a 10% w/w application of Shorea Robusta Resin produced a significant increase in wound contraction observed on the 2nd, 4th, and 6th day post-application.
- 02 At a higher concentration of 30% w/w, the resin demonstrated a significant and dose-dependent increase in wound contraction in rats, with effects evident on the 2nd, 4th, 6th, and 8th day, surpassing the efficacy observed at 10% w/w.
- 03 Ethanolic extracts and various fractions of Shorea Robusta exhibited promising antimicrobial activity against a spectrum of bacterial and fungal pathogens, with effective concentrations ranging from 10 to 50 mg/ml.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
The raw resin naturally presents with an acidic pH. For stable formulation, it readily incorporates into oil-based carriers, such as Carthamus tinctorius oil, and can be efficiently blended with beeswax at approximately 60°C for robust ointment preparations.
Safety
Safety Profile
Shorea Robusta Resin extract is generally considered safe for topical application within cosmetic formulations, with reported side effects and adverse reactions being uncommonly observed. It has received FDA designation for specific, limited food uses and was classified by Environment Canada as not anticipated to be toxic or harmful.
Your Skin
Skin Compatibility
Our Assessment
Verdict
With compelling clinical data supporting wound healing and antimicrobial benefits, combined with proven antioxidant activity, broad skin compatibility (suitable for all skin types), and a low irritancy/comedogenicity profile, Shorea Robusta Resin is a valuable active ingredient for advanced skincare formulations.
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References
Sources