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Moumoujus

SH-POLYPEPTIDE-92.

Valuable / SKIN CONDITIONING

SH-POLYPEPTIDE-92 is a synthetic polypeptide recognized for its potential as an active ingredient in advanced skincare formulations. It is understood to function similarly to other SH-polypeptides, acting as a cell signaling protein or growth factor to stimulate various cellular processes critical for skin health and rejuvenation.

Summary

Anti-aging Skin Renewal Collagen Stimulation Elastin Stimulation Wound Healing Support Elasticity Enhancer Hydration Support

Science

Mechanism of Action

This polypeptide is believed to function as a cellular messenger, influencing key dermal processes. Drawing parallels with related SH-polypeptides (e.g., SH-Polypeptide-1, -5, -9), it is hypothesized to stimulate cellular activities such as accelerating skin cell turnover, boosting the synthesis of structural proteins like collagen and elastin, and supporting the skin's natural wound healing mechanisms. These actions collectively aim to enhance skin elasticity, promote overall skin renewal, and improve epidermal hydration.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Unknown
Optimal pH N/A
0 7 14

Stability

As a recombinant peptide with a relatively large molecular structure, SH-POLYPEPTIDE-92 likely requires sophisticated delivery systems, such as liposomes or nanoparticles, to optimize its stability, penetration, and efficacy within topical applications. Peptides are generally susceptible to physicochemical degradation, necessitating protective formulation strategies to maintain product shelf-life and ingredient integrity.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

Specific safety assessments by CIR or SCCS for SH-POLYPEPTIDE-92 are not available. The FDA mandates cosmetic ingredient safety but does not pre-approve them. However, safety studies on related peptides, such as SH-Polypeptide-1, applied topically have shown no significant irritation, general toxicity, or adverse effects. Paula's Choice identifies SH-POLYPEPTIDE-92 as 'generally non-irritating', aligning with the expectation that manufacturers ensure adherence to broader cosmetic safety regulations for peptides.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

SH-POLYPEPTIDE-92 is a valuable polypeptide that, through its inferred growth factor activity, holds significant promise for promoting skin rejuvenation and improving skin structural integrity, with a low risk of irritation.

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