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Moumoujus

SH-POLYPEPTIDE-78.

Valuable / SKIN CONDITIONING

SH-POLYPEPTIDE-78 is a sophisticated synthetic peptide engineered to support cellular communication within the skin, promoting its natural renewal processes and enhancing resilience. For hair, it actively fortifies keratin structure, boosting strength, elasticity, and protection against degradation, complemented by antioxidant and antibacterial properties.

Summary

Peptide Hair Conditioning Skin Conditioning Antioxidant Antibacterial Keratin Stabilization Hair Strength & Elasticity Enhancer Skin Renewal Support Cellular Communication Modulator Surfactant - Cleansing

Science

Mechanism of Action

This bioactive peptide is designed to mimic specific signaling sequences found in the extracellular matrix of the skin. Upon topical application, it interacts with skin cell receptors to modulate cellular communication pathways essential for maintaining skin homeostasis. By positively influencing key proteins within the dermal environment, SH-POLYPEPTIDE-78 contributes to the optimization of the skin's inherent renewal processes, supporting a visibly smoother and more resilient complexion.

Research

Clinical Evidence

Medium confidence
Effective range 0.005–5%
Optimal

N/A

Key findings

  1. 01 For general hair care formulations, recommended concentrations range from 0.005% to 0.05%.
  2. 02 In rinse-off products such as shampoos and conditioners, a concentration of 0.5% to 2% is suggested.
  3. 03 High-potency hair serums and ampoules typically utilize higher concentrations, between 2% and 5%.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH 5 – 6.5
0 7 14

Stability

Optimal stability for this peptide in hair care formulations is achieved within a pH range of 5.0 to 6.5. For short-term storage, preservation at 2℃ to 8℃ is recommended, while long-term storage requires -20℃±5℃. It must be protected from direct sunlight, heat, and moisture to maintain its integrity.

Synergies

  • Can be explored for synergistic use with Minoxidil to potentially enhance anti-DHT effects.

Conflicts

  • Compatibility testing with Minoxidil is recommended to ensure formulation stability and efficacy, as potential issues have been noted.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

SH-POLYPEPTIDE-78 has not been formally reviewed by regulatory bodies such as CIR, SCCS, or FDA. While some sources indicate general safety for hair applications without reported adverse side effects, a comprehensive regulatory assessment is currently unavailable.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

SH-POLYPEPTIDE-78 offers valuable multi-functional benefits for both skin vitality and hair integrity, supported by concentration recommendations for various hair applications, though further independent safety and efficacy data would strengthen its profile.

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