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Moumoujus

SH-POLYPEPTIDE-77.

Valuable / SKIN CONDITIONING

SH-POLYPEPTIDE-77 is a bio-identical synthetic human peptide, identified as glutaredoxin-1, engineered to provide advanced skin conditioning and potent antioxidant benefits. It actively reinforces the skin's inherent defense mechanisms, neutralizing environmental pollutants and oxidative stressors to protect vital structural components like collagen, elastin, and hyaluronic acid.

Summary

Skin Conditioning Antioxidant Anti-Aging Regenerating Firming Elasticity Enhancer

Science

Mechanism of Action

Functioning as a sophisticated signaling peptide, SH-POLYPEPTIDE-77 works by stimulating the skin's endogenous repair mechanisms and promoting regeneration, particularly in mature skin. Its protective action involves disarming damaging particles and bolstering natural antioxidant systems. This comprehensive approach strengthens the skin's structure, enhances elasticity, improves overall complexion, and contributes to a visible reduction in the appearance of wrinkles.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Unknown
Optimal pH N/A
0 7 14

Stability

As a large polypeptide, SH-POLYPEPTIDE-77 may benefit from advanced delivery systems such as liposomes or PLGA-coated nanoparticles to optimize its stability, enhance skin penetration, and maximize topical efficacy.

Safety

Safety Profile

CIR Status
Safe as used
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel has assessed a broad category of synthetic human peptides, including SH-POLYPEPTIDE-77, deeming them safe for use in current cosmetic practices and concentrations. This aligns with EU cosmetic regulations, which do not restrict these ingredients. Furthermore, the FDA considers peptones, a wider classification, as generally recognized as safe (GRAS) for direct food consumption.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

This bio-identical peptide offers comprehensive antioxidant protection and supports skin's natural regeneration and structural integrity across all skin types.

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