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Moumoujus

SH-OLIGOPEPTIDE-73 AMIDE ACETATE.

Valuable / SKIN CONDITIONING, SKIN PROTECTING

SH-Oligopeptide-73 Amide Acetate is a synthetic biomimetic peptide engineered to support the skin's natural processes, enhancing barrier resilience and overall skin health. It functions primarily as a skin conditioning agent, promoting a soft, smooth, and hydrated complexion, while simultaneously offering protective benefits against environmental stressors.

Summary

Skin Conditioning Skin Protecting Barrier Support Hydration Soothing

Science

Mechanism of Action

This synthetic ingredient is designed to precisely mimic Substance P, an endogenous human protein composed of 11 amino acids. By emulating Substance P, SH-Oligopeptide-73 Amide Acetate actively supports the skin's inherent functions, leading to a fortified and more resilient skin barrier. Its action contributes to maintaining optimal skin hydration and texture, and it forms a protective layer, shielding the skin from external aggressors such as pollution and UV radiation, thereby mitigating the risk of irritation and inflammation.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Demonstrates significant skin conditioning properties, maintaining skin softness, smoothness, and hydration.
  2. 02 Supports the skin's natural barrier processes, enhancing resilience through its mimicry of Substance P.
  3. 03 Provides robust skin protection against environmental stressors, contributing to a reduction in irritation and inflammation.
  4. 04 Preliminary research (BETA status) suggests potential for stimulating collagen synthesis and visibly reducing the appearance of fine lines and wrinkles.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

The ingredient is converted into its acetate salt form, which significantly improves its solubility and facilitates its seamless integration into diverse skincare formulations. Its production via solid-phase peptide synthesis (SPPS) ensures high stability and consistent quality for cosmetic applications.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

Generally regarded as safe for topical cosmetic use. However, specific data concerning its safety during pregnancy and breastfeeding is currently insufficient, thus professional medical advice is recommended. While considered low risk, minor side effects such as skin irritation or redness are possible, making a preliminary patch test advisable before comprehensive application. The CIR Expert Panel has not yet assessed this ingredient.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

SH-Oligopeptide-73 Amide Acetate is a valuable peptide, offering robust skin conditioning, barrier support, and environmental protection with a low risk of irritation, making it suitable for all skin types.

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