Get a Free 5ml Mini Now Free 5ml Mini With Every Order of The Mantle

SH-OCTAPEPTIDE-4.

Valuable CAS - / ANTI-SEBORRHEIC, ANTIOXIDANT, CHELATING, REDUCING, SKIN PROTECTING

SH-OCTAPEPTIDE-4 is a synthetic 8-amino acid neuropeptide, mimicking a naturally occurring protein fragment, designed to bolster the skin's natural defenses. It offers multiple benefits, including regulating sebum production, providing antioxidant protection, and strengthening the skin barrier against environmental stressors.

Anti-seborrheic Antioxidant Chelating Reducing Skin protecting Anti-aging Anti-wrinkle Rejuvenating Skin regeneration Wound-healing

Science

This precision-engineered neuropeptide functions by signaling the skin to modulate its responses to various harmful stimuli such as irritation, heat, or cold, while activating endogenous repair mechanisms. It effectively reduces excessive sebum production, acts as a potent antioxidant to neutralize free radicals, and possesses a chelating ability to bind heavy metals. Furthermore, it reinforces the skin's structural integrity and barrier function, promoting regeneration and visibly reducing signs of aging, including wrinkles.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Peptides like SH-OCTAPEPTIDE-4 generally exhibit limited stability and a short half-life, making them susceptible to rapid degradation. To enhance their proteolytic stability and improve bioavailability, advanced formulation techniques such as lipidization, PEGylation, or glycosylation are frequently employed. Stability can also be influenced by the peptide's specific amino acid sequence and its resistance to enzymatic cleavage. This peptide is noted to be compatible with various moisturizing, thickening, and functional ingredients, alongside plant essences.

Synergies

  • moisturizing agents
  • thickening agents
  • functional molecules
  • plant essences

Safety

CIR Status
Not reviewed
Sensitization risk Low

While SH-OCTAPEPTIDE-4 is generally considered safe for topical cosmetic use, formal safety assessments by authoritative bodies such as CIR, SCCS, or FDA have not been explicitly conducted or published for this specific octapeptide. Reviews exist for other peptides, but a dedicated evaluation for SH-OCTAPEPTIDE-4 is currently unavailable.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

SH-OCTAPEPTIDE-4 is a valuable, multi-functional peptide that offers significant benefits including anti-aging, sebum regulation, antioxidant action, and environmental protection, proving suitable for all skin types despite the current absence of detailed clinical efficacy data at specific concentrations.


Related

Finding similar ingredients…