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SH-OCTAPEPTIDE-2.

Insufficient Data / SKIN CONDITIONING, SKIN PROTECTING

SH-Octapeptide-2 is a biomimetic peptide designed to emulate the natural growth factor thymosin-β4. It is known for its potential to stimulate hair growth and offers multifaceted benefits for skin, including regeneration and structural strengthening.

Hair Growth Promotion Skin Conditioning Skin Protection Anti-aging Skin Regeneration

Science

This peptide acts by activating the stem cells within hair follicles, which reduces cell death (apoptosis) and increases the proliferation of keratinocytes. For skin, SH-Octapeptide-2 contributes to conditioning and protection, stimulating cellular regeneration, and fortifying skin structure, thereby potentially diminishing the appearance of wrinkles.


Research

Low confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 In studies, SH-Octapeptide-2 has been shown to promote hair growth by activating the stem cells of hair follicles and enhancing cell growth and migration, with effective concentrations noted between 0.0025% and 0.005%. Specific clinical efficacy data demonstrating skin benefits at defined concentrations is currently unavailable.

Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Stability

SH-Octapeptide-2 demonstrates enhanced stability and skin permeation when compared to natural thymosin-β4. However, general peptide stability can be compromised by exposure to high pH environments and elevated temperatures.


Safety

CIR Status
Not reviewed
Sensitization risk Unknown

Formal safety reviews by regulatory bodies such as the Cosmetic Ingredient Review (CIR), Scientific Committee on Consumer Safety (SCCS), or FDA have not been publicly documented for SH-Octapeptide-2. It is present on various retailer compliance lists, but detailed safety assessments from these agencies are not readily accessible.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Insufficient Data

While SH-Octapeptide-2 presents a compelling mechanism for skin regeneration and anti-aging, specific clinical efficacy data for skin applications remains limited, and comprehensive regulatory safety assessments are pending.


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