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SH-NONAPEPTIDE-2.

Insufficient Data / SKIN CONDITIONING

SH-NONAPEPTIDE-2 is a bioactive peptide, also recognized as Insulin-like growth factor 1, designed to promote cellular proliferation and aid in wound healing. It targets key anti-aging pathways and stimulates the production of vital extracellular matrix components like hyaluronic acid, revitalizing skin.

skin conditioning wound healing anti-aging cell proliferation extracellular matrix support collagen stimulation skin barrier strengthening hyaluronic acid production

Science

This peptide functions by activating the AKT signaling pathway, a crucial cascade involved in cellular longevity and preventing age-related decline. It stimulates cell proliferation and aids in the formation of new blood vessels, essential for detoxifying aged cells by facilitating the removal of CO2 and waste products. Furthermore, SH-NONAPEPTIDE-2 enhances the biosynthesis of hyaluronic acid and other extracellular matrix components, contributing to skin plumpness and structure, while also being claimed to boost collagen production and strengthen the skin barrier.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Unknown
Optimal pH N/A
0 7 14

Safety

CIR Status
Insufficient data
Sensitization risk Unknown

A specific safety assessment by CIR, SCCS, or FDA for SH-NONAPEPTIDE-2 (or SH-Oligopeptide-2) is not available. The CIR panel broadly considers peptides safe for topical application, typically at concentrations below 10 parts per million (ppm), though cautions are noted for elastin-derivatives and use on compromised skin.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Insufficient Data

SH-NONAPEPTIDE-2 presents promising mechanisms for anti-aging and skin revitalization, yet specific clinical efficacy data and a comprehensive safety assessment remain insufficient for a definitive scientific verdict.


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