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Moumoujus

SH-HEPTAPEPTIDE-9 SP.

Valuable / SKIN CONDITIONING - MISCELLANEOUS

SH-HEPTAPEPTIDE-9 SP is a precision-engineered peptide designed to target multiple signs of skin aging by stimulating essential regenerative processes. It enhances the skin's structural integrity, promoting a firmer, smoother, and more youthful complexion.

Summary

Anti-aging Wrinkle Reduction Collagen Synthesis Stimulation Elastin Production Enhancement Epidermal Regeneration Skin Barrier Support Increased Skin Elasticity Enhanced Skin Firmness Hydration Enhancement

Science

Mechanism of Action

This ingredient, categorized as an oligopeptide, functions by delivering short chains of amino acids to the skin. It stimulates regenerative processes within the deeper layers of the epidermis, reinforcing the skin's natural structure and barrier. SH-HEPTAPEPTIDE-9 SP, through its related form Acetyl Heptapeptide-9, mimics the action of Transforming Growth Factor beta (TGFβ). This crucial cytokine aids in skin recovery and wound healing, prompting skin fibroblasts to boost the production of collagen, elastin, and other extracellular matrix (ECM) components. This comprehensive stimulation enhances dermal cellular metabolism, leading to increased hydration, improved elasticity, and a visibly rejuvenated skin appearance.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

0.002%

Transparency

Dusting Analysis

Not commonly dusted

No specific data regarding dusting analysis for SH-HEPTAPEPTIDE-9 SP was found in the research.

The Formula

Formulation

Solubility
Water
Optimal pH 5 – 7
0 7 14

Stability

Related Acetyl Heptapeptide-9 is a synthetic, N-terminally acetylated peptide, a modification that enhances its stability against enzymatic degradation. This structural engineering supports reliable performance during manufacturing, storage, and consumer use. A pH range of 5.0-7.0 is optimal for the stability of related Hexapeptide-9.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

Specific safety assessments by CIR, SCCS, or FDA for SH-HEPTAPEPTIDE-9 SP, Acetyl Heptapeptide-9, or SH-Polypeptide-9 are currently unavailable. General peptide reviews by CIR broadly indicate safety for topical use at concentrations below 0.001% (10 ppm), though with general cautions regarding elastin-derived peptides and potential unknown safety profiles on compromised or damaged skin. Due to the lack of specific review for this exact peptide, a definitive safety profile cannot be fully established from the provided data.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

SH-HEPTAPEPTIDE-9 SP is a promising anti-aging peptide that, based on robust evidence from related compounds, effectively reduces wrinkles and enhances skin structure by promoting collagen and elastin production.

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