Science
Mechanism of Action
This synthetic peptide, also known as Heptapeptide-7, operates by emulating Epidermal Growth Factor (EGF), stimulating keratinocyte proliferation and migration critical for re-epithelialization and wound healing. It significantly boosts collagen production by fibroblasts and supports the intricate remodeling of the extracellular matrix (ECM). Furthermore, it activates fibroblast communication and upregulates genes vital for growth factors and ECM components. SH-HEPTAPEPTIDE-7 SP also reinforces the Dermal-Epidermal Junction (DEJ) by stimulating crucial junction proteins such as collagen IV, VII, and XVII, thereby enhancing cellular adhesion and skin cohesion, especially beneficial for aging skin.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
No data available in research to suggest this ingredient is commonly 'dusted' or used at ineffective concentrations to mislead consumers.
The Formula
Formulation
Stability
The ingredient is supplied within phospholipid mini-vesicles, a sophisticated delivery system that significantly enhances its permeation and prolongs its bioavailability in the skin. This contributes to its excellent stability and compatibility across a range of advanced anti-aging formulations, including serums and creams.
Safety
Safety Profile
No specific regulatory information for Gransome Heptapeptide-7 (Heptapeptide-7 in phospholipid mini-vesicles) is publicly available. However, the raw material is claimed to cause no skin or eye irritation, indicating a low sensitization risk.
Your Skin
Skin Compatibility
Our Assessment
Verdict
SH-HEPTAPEPTIDE-7 SP is a valuable regenerative peptide, offering multi-faceted benefits for aging skin by enhancing Dermal-Epidermal Junction integrity, stimulating collagen, and improving overall skin texture and wrinkle appearance.
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