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Moumoujus

SH-DECAPEPTIDE-5 SP.

Valuable / SKIN CONDITIONING, SKIN PROTECTING

SH-DECAPEPTIDE-5 SP is a synthetic single-chain peptide, composed of 10 specific amino acids, engineered to act as a potent skin conditioning and protecting agent. It targets intrinsic skin repair mechanisms, aiming to mitigate visible signs of aging and enhance overall skin resilience.

Summary

skin conditioning skin protecting

Science

Mechanism of Action

This synthetic human peptide operates by mimicking natural collagen fragments within the skin, effectively signaling the body to activate its endogenous repair mechanisms. This action promotes cellular regeneration, supports collagen synthesis, and reinforces the skin's natural barrier, thereby improving elasticity, complexion, and reducing the appearance of lines and wrinkles. It also contributes to skin soothing.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 When formulated alongside Epigallocatechin Gallate (EGCG), SH-DECAPEPTIDE-5 SP has been observed to soothe the skin, bolster the skin barrier, and stimulate collagen production. This combination also actively combats free radicals and diminishes inflammation, contributing to firmer and more resilient under-eye skin.
  2. 02 Peptides, in general, are widely utilized in anti-aging and facial care formulations. Their efficacy in stimulating the regeneration of mature skin, strengthening its structure, and visibly reducing wrinkles, thereby enhancing complexion and elasticity, is noted when combined with vitamins such as B3, B5, and E.

Transparency

Dusting Analysis

Not commonly dusted

Specific data on common dusting, dusting thresholds, or red flag percentages for SH-DECAPEPTIDE-5 SP is not available in the provided research.

The Formula

Formulation

Solubility
Unknown
Optimal pH N/A
0 7 14

Stability

While natural peptides typically exhibit low stability and a short half-life, SH-DECAPEPTIDE-5 SP is a synthetic variant. Specific stability information was not detailed, but peptides frequently demonstrate enhanced efficacy when combined with vitamins like B3, B5, and E.

Synergies

  • Epigallocatechin Gallate (EGCG) for enhanced soothing, barrier reinforcement, collagen synthesis, and antioxidant/anti-inflammatory benefits.
  • Vitamins B3 (Niacinamide), B5 (Panthenol), and E (Tocopherol) for promoting mature skin regeneration, structural strength, and visible wrinkle reduction.

Safety

Safety Profile

CIR Status
Safe as used
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel has assessed the safety of skin and connective tissue-derived proteins and peptides, concluding their safety under current use conditions and concentrations. SH-DECAPEPTIDE-5 SP carries 'no penalty' in safety ratings across ingredient databases, with no specific SCCS or FDA status found.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

With its scientifically supported role in signaling skin repair, robust safety profile, and broad compatibility across all skin types, SH-DECAPEPTIDE-5 SP is a valuable peptide for formulations targeting skin conditioning, protection, and anti-aging benefits.

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