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Moumoujus

SH-DECAPEPTIDE-2.

Insufficient Data / SKIN CONDITIONING

SH-DECAPEPTIDE-2 is a synthetic signaling decapeptide engineered to enhance the skin's intrinsic repair capabilities. It works to improve overall skin health, promoting a softer, smoother, and more hydrated complexion, while also bolstering the skin's natural defenses.

Summary

Skin conditioning Skin protecting Anti-aging Collagen boosting Cell renewal Promotes wound healing

Science

Mechanism of Action

As a signaling peptide, SH-DECAPEPTIDE-2 activates the skin's endogenous repair mechanisms. This action stimulates cell proliferation and supports wound healing processes. It notably enhances fibroblast metabolism and can stimulate the synthesis of collagen, a crucial structural protein, while simultaneously inhibiting matrix metalloproteases, enzymes that can degrade the skin's extracellular matrix. This combined effect contributes to improved skin condition, resilience, and appearance.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

While a specific optimal pH range for SH-DECAPEPTIDE-2 is not detailed, the observed buffering capacity of other decapeptides, such as sh-Decapeptide-7, suggests that maintaining an optimal pH is essential for preserving the stability and efficacy of this peptide in cosmetic formulations.

Safety

Safety Profile

CIR Status
Insufficient data
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel has not conducted a specific safety assessment for SH-DECAPEPTIDE-2 or Decapeptide-2, leading to an 'insufficient data' status. Peptides in cosmeceuticals often occupy a 'gray area' as they are not formally recognized by the FDA. However, the CIR Panel has concluded many other 'Skin and Connective Tissue-Derived Proteins and Peptides' are safe for cosmetic use. Related peptides, like R-(Sh-Polypeptide-2 Decapeptide-40), are generally well-tolerated topically, with skin irritation, redness, or allergic reactions being rare occurrences.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Insufficient Data

SH-DECAPEPTIDE-2 holds promise for skin conditioning, protection, and anti-aging benefits based on general peptide mechanisms, but specific clinical data for this particular decapeptide is limited, warranting further research to confirm its precise efficacy.

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