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SH-DECAPEPTIDE-1 SR-PINEAPPLE STEM BROMELAIN.

Valuable / SKIN CONDITIONING

SH-DECAPEPTIDE-1 SR-PINEAPPLE STEM BROMELAIN, also known as NX35™ Sculpt Technology, is a sophisticated biomimetic complex designed to precisely target cellular functions for enhanced skin architecture. This innovative blend combines a synthetic signaling peptide with the proteolytic enzymes of pineapple stem bromelain to optimize skin contour and vitality.

Summary

Skin Conditioning Antioxidant Exfoliant Anti-inflammatory Facial Contouring Skin Sculpting Lipogenesis Inhibition Anti-aging Skin Rejuvenation Antimicrobial Skin Softening Reduces Water Retention Collagen Modulation

Science

Mechanism of Action

Operating as a biomimetic exosome technology, this complex delivers coded instructions to skin cells, actively reprogramming cellular activity to correct imbalances. The SH-Decapeptide-1 peptide component supports the skin's natural protein synthesis, including collagen, while the SR-Pineapple Stem Bromelain, a potent proteolytic enzyme, provides enzymatic exfoliation, calms inflammation, and exhibits antimicrobial actions against specific skin pathogens like S. aureus and P. acne. Furthermore, it aids in inhibiting lipogenesis and diminishing localized facial fat deposits, contributing to a refined facial contour. Its unique ability to modulate collagen levels also supports skin softening and can reduce dermal thickness.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Demonstrated efficacy in facial contouring and sculpting by targeting fat cells, inhibiting lipogenesis, and reducing facial fat and water retention.
  2. 02 Bromelain, a key component, exhibits robust anti-inflammatory and anti-edematous properties, crucial for soothing skin.
  3. 03 In a clinical study, bromelain delivered via a niosomal hydrogel led to a significant 37% reduction in mean dermal thickness (from 1195 μm to 750 μm) over two months in scleroderma patients, concurrently improving skin softness by decomposing excess collagen.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH 6 – 10
0 7 14

Stability

The enzymatic activity of bromelain is pH-dependent, maintaining optimal function within a pH range of 6.0 to 10.0, with peak activity observed around pH 7.0 and a secondary peak at pH 10.0. Activity is irreversibly lost above pH 10.0. Given bromelain's isoelectric point (pI) of 4.6, it is negatively charged at typical formulation pH values (e.g., 5.0 and 6.5), ensuring compatibility with anionic systems.

Safety

Safety Profile

CIR Status
Insufficient data
Sensitization risk Low

While comprehensive regulatory status for the combined complex is currently under evaluation, individual component data suggests a favorable safety profile. Stem bromelain is widely regarded as a safe and effective phytotherapeutic agent with a low incidence of undesirable effects, even with prolonged use. Products formulated with SH-DECAPEPTIDE-1 SR-PINEAPPLE STEM BROMELAIN have been categorized as '100 Free' from common allergens, indicative of a low irritancy potential.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

A multi-functional biomimetic complex, SH-DECAPEPTIDE-1 SR-PINEAPPLE STEM BROMELAIN offers significant benefits for facial contouring, skin rejuvenation, and exfoliation, making it a valuable active ingredient.

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