SEMPERVIVUM TECTORUM EXTRACT.

The extract's bioactivity is primarily attributed to its complex profile of polyphenols, tannins, and saponins. Flavonoids, such as Rutin, provide robust antioxidant defense and help stabilize capillary walls, while Hyperoside actively mitigates inflammation by modulating pro-inflammatory cytokines like TNF-α and IL-6. Tannic acid imparts an astringent effect, aiding in skin tightening and minimizing exudation in minor dermal imperfections. Oleanolic acid contributes mild antibacterial properties against common skin flora, including Staphylococcus aureus. Saponins may enhance the dermal absorption of other active ingredients by increasing cell membrane permeability. Furthermore, the extract efficiently scavenges free radicals, forms a protective barrier on the skin, and significantly improves hydration by stimulating metabolic processes and increasing glucose uptake. Its unique antagonistic activity on TRPV1 receptors can alleviate irritation and pain, complemented by agonistic activity on cannabinoid receptor type 1 (CB1), fostering a balanced skin environment. The extract also actively supports skin healing and has demonstrated the capacity to inhibit tyrosinase activity, contributing to a more even skin tone and reduced melanin synthesis.