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Moumoujus

SEDUM SARMENTOSUM EXTRACT.

Valuable CAS - / HUMECTANT

Sedum Sarmentosum Extract is a botanical ingredient recognized for its comprehensive benefits in skincare, particularly its capacity to enhance skin hydration. It actively supports the skin's natural moisturizing processes while concurrently providing significant antioxidant, anti-inflammatory, and brightening effects. Its soothing properties make it a versatile asset for maintaining skin health and balance.

Summary

Moisturizer Humectant Antioxidant Anti-inflammatory Brightening Soothing Anti-aging Acne-alleviating Antimicrobial Barrier Support

Science

Mechanism of Action

This extract functions primarily as a moisturizer by elevating the expression of hyaluronan synthase (HAS) genes, specifically HAS-2 and HAS-3, which stimulates endogenous hyaluronan (HA) production within keratinocytes. Beyond hydration, it exhibits anti-inflammatory, antimicrobial, and potent antioxidant properties. It also contributes to skin brightening by inhibiting the expression of tyrosinase and TRP-1 enzymes.

Research

Clinical Evidence

Medium confidence
Effective range 0.001–30%
Optimal

0.01-5% by weight

Key findings

  1. 01 Topical application to human skin has demonstrated a measurable increase in skin hydration and a notable decrease in transepidermal water loss (TEWL), indicating enhanced barrier function.
  2. 02 In cosmetic formulations, particularly when stabilized with a water-soluble lipoic acid-PEG conjugate, this extract has shown efficacy across multiple concerns including anti-wrinkle action, skin brightening, irritation relief, and acne alleviation.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Chemical stability can be notably improved when Sedum sarmentosum extract is formulated alongside a water-soluble lipoic acid-PEG conjugate.

Synergies

  • Lipoic acid-PEG conjugate (for enhanced stability and broader efficacy)

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

EWG Skin Deep assesses Sedum Sarmentosum Extract with low concerns for cancer, allergies, and immunotoxicity. Paula's Choice indicates that it is generally considered non-irritating for topical use.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Sedum Sarmentosum Extract is a valuable multi-active ingredient, offering proven hydration enhancement and barrier support, alongside significant antioxidant, brightening, and anti-inflammatory benefits suitable for all skin types.

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