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Moumoujus

SEDUM ROSEA ROOT EXTRACT.

Valuable CAS 92457-37-9 / ANTIOXIDANT, ASTRINGENT, SKIN CONDITIONING

Sedum Rosea Root Extract, synonymous with Rhodiola rosea, is a potent adaptogenic botanical recognized for its comprehensive benefits in skin resilience and rejuvenation. Rich in active compounds like rosavin and salidroside, it provides significant antioxidant, anti-inflammatory, and conditioning support, enabling skin to adapt to stressors and maintain optimal balance.

Summary

antioxidant astringent skin conditioning anti-inflammatory adaptogen anti-aging soothing barrier support hydrating

Science

Mechanism of Action

This extract operates through multiple pathways to enhance skin health. Its primary compounds, including rosavin, salidroside, flavonoids, and proanthocyanidins, function as powerful antioxidants, effectively neutralizing free radicals to protect the skin from oxidative stress and environmental aggressors. It also exhibits anti-inflammatory properties, soothing irritation and redness by potentially stimulating the release of relaxing beta-endorphins, which makes it beneficial for managing inflammatory conditions like acne. As an adaptogen, it assists the skin in building resilience against daily environmental and internal stressors. Furthermore, it supports anti-aging and skin conditioning by promoting collagen production, strengthening the skin's protective barrier, maintaining hydration, diminishing the appearance of fine lines, and stimulating tissue metabolism. The extract also possesses astringent qualities.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 An in-vitro study utilizing a BV2 microglial cell model demonstrated anti-inflammatory activity at a concentration of 50 µg/mL. However, specific topical concentrations and comprehensive human clinical trial data regarding efficacy for skin care are currently limited.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Sedum Rosea Root Extract is primarily water-soluble or hydro-soluble, making it compatible with aqueous and hydroalcoholic extraction methods and subsequent formulations. Some active antioxidant compounds within the extract are also alcohol-soluble. It is noted to integrate well into emulsion and surfactant systems. While a precise optimal pH range for its stability in cosmetic formulations is not explicitly detailed, one study indirectly suggested better antioxidant stability around a lower pH of 6.0.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel has not specifically reviewed Sedum Rosea Root Extract for topical cosmetic applications. While related Rhodiola rosea ingredients have received 'Generally Recognized As Safe (GRAS)' status from the FDA, this primarily pertains to oral dietary supplements. For topical use, the ingredient is widely considered safe and well-tolerated, with no reported toxic effects or intolerance at normal usage levels, even for sensitive skin. The Environmental Working Group (EWG) rates common concerns such as cancer, allergies & immunotoxicity, developmental and reproductive toxicity, and use restrictions as LOW. SkinSAFE identifies it as 'Irritant Free'.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

Sedum Rosea Root Extract is a valuable botanical ingredient, offering broad-spectrum antioxidant, anti-inflammatory, and adaptogenic benefits for all skin types, supporting resilience and overall skin health despite limited human topical clinical dose data.

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