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Moumoujus

SECHIUM EDULE FRUIT EXTRACT.

Valuable CAS 223748-59-2 / SKIN CONDITIONING

Sechium Edule Fruit Extract, derived from the chayote fruit, is a versatile botanical ingredient renowned for its comprehensive skin benefits. Rich in potent antioxidants and anti-inflammatory compounds, it actively defends against environmental stressors while promoting hydration, supporting skin barrier integrity, and contributing to a more even skin tone. Its multi-functional profile makes it a valuable asset for precision skincare formulations.

Summary

Antioxidant Anti-inflammatory Moisturizing Photoprotective Skin Brightening Collagen Boosting Skin Conditioning Wound Healing Support

Science

Mechanism of Action

This extract operates through multiple pathways to enhance skin health. Its high concentration of phenolic compounds, flavonoids, and other bioactive molecules confers robust antioxidant activity, effectively neutralizing free radicals and mitigating oxidative stress. It demonstrates anti-inflammatory properties, reducing skin irritation. Furthermore, Sechium Edule Fruit Extract supports cellular regeneration and tissue repair by reducing matrix metalloproteinase-2 (MMP-2) levels and promoting collagen synthesis, crucial for skin structure. It also offers photoprotection by shielding keratinocytes from UVA-induced cytotoxicity, decreasing intracellular reactive oxygen species (ROS), and bolstering DNA repair mechanisms. For skin brightening, it inhibits tyrosinase activity, which is key to melanin production, and contributes to overall skin hydration.

Research

Clinical Evidence

Medium confidence
Effective range 0.5–5%
Optimal

0.5%

Key findings

  1. 01 In vitro studies confirm that a 1% (w/w) concentration of Sechium edule peel extract is non-cytotoxic to keratinocyte cells (HaCaT) at 100 μg/mL, demonstrating stability in gel formulations and potential for skin protection against oxidative stress and harmful radiation.
  2. 02 Formulations containing an optimal proportion range of 0.5-5.0% chayote extract have been shown to improve skin barrier function, increase skin hydration, and effectively inhibit tyrosinase activity, contributing to a skin brightening effect.
  3. 03 In a study on diabetic rats, a 60% cream significantly reduced matrix metalloproteinase-2 (MMP-2) levels and increased collagen density, indicating strong wound healing capabilities.

Transparency

Dusting Analysis

Not commonly dusted

Clinical studies indicate effective concentrations in the range of 0.5-5.0% for various skin benefits, and 1% for stability and cytoprotection, which are standard and not indicative of an ingredient being 'dusted' in formulations.

The Formula

Formulation

Solubility
Water
Optimal pH 5 – 7
0 7 14

Stability

Formulations incorporating Sechium Edule Fruit Extract exhibit good stability, with minimal pH fluctuations observed when stored at 8°C and 25°C for up to 30 days. Optimal stability is maintained within a pH range of 5.0 to 7.0, closely aligning with the natural pH of human skin (approximately 5.5-6.5).

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

While no specific Cosmetic Ingredient Review (CIR), SCCS, or FDA assessment for topical use is available, in vitro research indicates a non-cytotoxic profile for keratinocyte cells at concentrations up to 100 μg/mL. INCIDecoder rates its irritancy as low.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

Sechium Edule Fruit Extract is a valuable, multi-functional ingredient offering significant antioxidant defense, hydration, and support for skin regeneration and brightening, making it suitable for a wide range of precision skincare formulations.

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