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SCUTELLARIA LATERIFLORA EXTRACT.

Valuable CAS 90106-67-5 / SKIN CONDITIONING

Scutellaria Lateriflora Extract is a botanical active, notable for its rich flavonoid content which provides potent antioxidant and anti-inflammatory benefits. It acts as a comprehensive skin conditioner, offering protection against oxidative stress, soothing irritation, promoting regeneration, and addressing signs of aging and hyperpigmentation.

Summary

Antioxidant Anti-inflammatory Antimicrobial Skin Conditioning Skin Regeneration Hydrating Skin Brightening Anti-aging UV Protection (adjunctive) Cortisol Modulation (in vitro)

Science

Mechanism of Action

This extract exerts its skin benefits through a multifaceted mechanism, primarily due to its high concentration of flavonoids like baicalin, baicalein, oroxylin A, and wogonin. These compounds function as powerful antioxidants, neutralizing free radicals and mitigating oxidative stress. Concurrently, it exhibits significant anti-inflammatory and antimicrobial actions, crucial for calming irritated skin and managing inflammatory conditions. Furthermore, it supports cellular regeneration, enhances skin hydration, helps inhibit melanin synthesis for a brighter complexion, and potentially preserves collagen integrity, thus addressing visible signs of aging. Initial data also suggests some protective capacity against UV-induced damage.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

This plant extract, rich in polyphenolic compounds, demonstrates low stability and is sensitive to degradation by light and heat. To preserve its efficacy in cosmetic formulations, protective techniques such as encapsulation are recommended. Common extract preparations utilize water, glycerin, and ethanol.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Moderate

While generally considered safe for internal therapeutic use, modern topical research is limited. Internal over-dosage has been linked to severe adverse neurological effects. A notable concern is potential adulteration with hepatotoxic plants like germander. For topical applications, individuals with sensitive skin should conduct a patch test, as mild irritation or allergic reactions are possible. This ingredient is not an FDA-approved drug but is utilized in various over-the-counter formulations.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Scutellaria Lateriflora Extract offers a broad spectrum of potential benefits, including antioxidant, anti-inflammatory, and regenerative properties, making it a versatile ingredient, though specific topical clinical data is currently limited.

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