Science
Mechanism of Action
This extract operates through multiple mechanisms on the skin. Its anti-inflammatory effects are attributed to compounds like glutinol and glutinone, which decrease pro-inflammatory cytokines such as IFN-γ and IL-6 while concurrently elevating anti-inflammatory IL-10 levels. Antioxidant activity is demonstrated by the upregulation of crucial antioxidative enzymes, including superoxide dismutase (SOD), glutathione peroxidase (GPx), and glutathione reductase (GRd). Furthermore, it appears to promote wound healing by accelerating skin closure, potentially through enhanced collagen synthesis, and exhibits broad-spectrum antimicrobial activity against both bacterial (e.g., E. coli, Staph. aureus) and fungal strains. These actions are primarily driven by its rich composition of flavonoids, terpenoids, and glutinol.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
Information regarding dusting analysis for this ingredient is not available in the provided research data.
The Formula
Formulation
Stability
No specific optimal pH range or stability notes for cosmetic formulations were identified in the research data.
Safety
Safety Profile
The safety of Scoparia Dulcis Flower/Leaf/Stem Extract for cosmetic use has not been specifically reviewed by regulatory bodies such as CIR, SCCS, or FDA. Oral administration of an ethanolic extract in rats indicated low toxicity, with an LD50 of 2738.61 mg/kg. In vitro studies on Vero cells demonstrated low cytotoxicity, with cell viability exceeding 80% at concentrations up to 250 µg/mL. The plant has historically been regarded as safe in traditional medicinal applications.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Scoparia Dulcis Flower/Leaf/Stem Extract is a valuable botanical ingredient, demonstrating a broad spectrum of in vitro benefits including powerful antioxidant, anti-inflammatory, and antimicrobial actions, making it a promising addition for diverse skincare formulations.
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References
Sources