Science
Mechanism of Action
This extract exerts its antioxidant effects through the synergistic action of phenolic compounds, flavonoids, and tannins, which neutralize free radicals to protect cellular integrity. Its anti-inflammatory capacity is driven by the inhibition of critical inflammatory cytokines, specifically TNF-α and ASK1. Furthermore, its antibacterial activity targets skin pathogens, including Propionibacterium acnes, attributed to the presence of alkaloids and flavonoids. The extract also demonstrates potential to reduce sebum production via lipoxygenase inhibition, diminish the appearance of hyperpigmentation (such as sun spots and melasma), and reduce fine lines and wrinkles by inhibiting MMP-1 activity.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 Isolated compounds from Schkuhria Pinnata exhibited significant anti-inflammatory activity, inhibiting TNF-α and ASK1 cytokines with IC50 values of 19.08 nM and 8.94 nM, respectively.
- 02 Various extracts demonstrated antimycobacterial activity against Mycobacterium smegmatis.
Transparency
Dusting Analysis
The Formula
Formulation
Safety
Safety Profile
Schkuhria Pinnata Extract has not been specifically evaluated by the Cosmetic Ingredient Review (CIR) Expert Panel or the Scientific Committee on Consumer Safety (SCCS), indicating a lack of comprehensive safety assessments for cosmetic application.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Schkuhria Pinnata Extract is a valuable botanical ingredient demonstrating broad-spectrum benefits including antioxidant, anti-inflammatory, and antibacterial properties, though further human clinical data is needed to solidify optimal topical concentrations for all proposed skin applications.
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