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SCHIZANDRA NIGRA FRUIT EXTRACT.

Valuable CAS - / SKIN CONDITIONING

Schizandra Nigra Fruit Extract is a potent botanical powerhouse, recognized for its adaptogenic and multi-functional properties. Rich in antioxidants and bioactive compounds, it is formulated to help skin adapt to environmental stressors, enhance resilience, and promote a visibly healthier, more radiant complexion.

Summary

Antioxidant Skin-conditioning Anti-inflammatory Barrier support Collagen boosting Brightening Antimicrobial Adaptogenic

Science

Mechanism of Action

This extract delivers a comprehensive action profile through its array of compounds, including lignans, schisandrin, essential fatty acids, and vitamins C & E. These constituents function as powerful antioxidants, neutralizing free radicals and shielding skin from environmental aggressors. Lignans are particularly effective at calming inflammation and supporting the skin's natural barrier. The extract boosts hydration by strengthening the lipid barrier, leading to improved moisture retention. It also stimulates collagen synthesis for enhanced skin firmness and elasticity, while its antimicrobial properties may help manage breakouts. Furthermore, its ability to significantly inhibit tyrosinase contributes to an anti-melanogenesis effect, promoting a more even skin tone. As an adaptogen, it equips the skin to better withstand daily stressors like pollution and UV exposure.

Research

Clinical Evidence

Medium confidence
Effective range 2–5%
Optimal

2-5%

Key findings

  1. 01 Formulations incorporating 2-5% of this extract are recommended for optimal results.
  2. 02 In vitro studies (primarily on *Schisandra chinensis*) demonstrated that at 50 µg/mL, a microwave-assisted extract induced up to a 150% increase in HaCaT cell proliferation without cytotoxic effects.
  3. 03 At 50 µg/mL (in vitro), strong tyrosinase inhibition was observed (96.2-98.5%), suggesting significant anti-melanogenesis and skin-whitening potential.
  4. 04 A 3% (w/w) concentration of *Schisandra chinensis* aqueous extract in body wash gels reduced skin irritation potential by up to 16%.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Aqueous extracts of *Schisandra chinensis* fruits, prepared using various methods (e.g., maceration, heat-assisted, microwave-assisted, ultrasound-assisted), indicate stability in aqueous systems, suggesting similar stability for *Schisandra nigra* extracts.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) has not specifically reviewed *Schisandra nigra* or *Schisandra chinensis* fruit extract for topical cosmetic use. Safety information predominantly refers to oral consumption of *Schisandra chinensis*. When taken orally, it is considered possibly safe for up to 12 weeks but may cause minor digestive issues or itching. It is possibly unsafe during pregnancy due to potential uterine contractions when ingested, and may interact with certain medications metabolized by CYP3A and P-gp substrates. There is currently no established maximum concentration for topical cosmetic use by regulatory bodies like CIR, SCCS, or FDA, and specific toxicity testing results for sensitive topical population subgroups are not available in the provided data. However, INCIDecoder rates its topical irritancy as low.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Schizandra Nigra Fruit Extract is a valuable ingredient, offering multi-faceted benefits from antioxidant protection and anti-inflammatory action to skin brightening and barrier strengthening, making it suitable for a wide range of skin types despite the limited specific *Nigra* topical safety data.

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