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Moumoujus

SCHISANDRA CHINENSIS FRUIT EXTRACT.

Valuable CAS 223748-53-6 / SKIN CONDITIONING

Schisandra Chinensis Fruit Extract is a multi-functional botanical renowned for its adaptogenic properties, enabling skin to better resist environmental stressors. It significantly enhances barrier function and moisture retention while delivering potent antioxidant and anti-inflammatory benefits, promoting a visibly calmer and more radiant complexion.

Summary

Antioxidant Soothing Barrier Support Adaptogenic Anti-aging Skin Brightening

Science

Mechanism of Action

This extract operates via multiple pathways to optimize skin health. It functions as an adaptogen, assisting the skin in adapting to diverse environmental stressors such as pollution and temperature shifts, thereby mitigating redness and irritation. Key compounds like lignans, polyphenols, and flavonoids provide robust antioxidant protection against free radical damage. Furthermore, it exhibits anti-inflammatory effects by modulating pathways such as COX-2/PGE2 and NF-κB, alongside reducing reactive oxygen species. Schisandra also strengthens the skin's protective barrier, improving moisture retention and preventing dryness. Specific components, like Schizandrin B, actively reduce collagen degradation by lowering MMP-1 expression and regulate superoxide dismutase (SOD) activity, contributing to anti-aging benefits. Its strong tyrosinase inhibitory activity supports anti-melanogenesis, promoting a more even skin tone.

Research

Clinical Evidence

High confidence
Effective range 0.05–40%
Optimal

N/A

Key findings

  1. 01 In vitro studies demonstrated a significant increase in keratinocyte growth, up to 150%, at a concentration of 50 µg/mL.
  2. 02 At 50 µg/mL, strong tyrosinase inhibitory activity was observed, with inhibition rates ranging from 96.2% to 98.5%.
  3. 03 Concentrations between 1.0 and 40 mg⋅mL−1 exhibited notable antioxidant capacity, ranging from 37% to 74% for the standard extract, and 63% to 79% for a fermented variant.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH 2.98 – 6.25
0 7 14

Stability

This extract maintains excellent stability within a weak acid pH range of 2.98 to 6.25 and exhibits strong heat stability. Formulations incorporating this extract showed no safety degradation after 60 days of storage.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

Generally considered safe for topical application. Individuals with highly sensitive skin or known allergies are advised to perform a patch test, as mild irritation or allergic reactions are possible, though infrequent.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Schisandra Chinensis Fruit Extract is a valuable ingredient, offering significant adaptogenic, antioxidant, and barrier-strengthening benefits for diverse skin types.

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