Science
Mechanism of Action
The essential oil component of this extract exerts antibacterial action by degrading bacterial cell walls, penetrating cell membranes, inhibiting critical enzyme functions, and depleting the proton motive force necessary for bacterial survival. Its robust antioxidant activity, indicated by DPPH inhibition, is attributed to a rich composition of terpenes and phenolic compounds. Furthermore, the extract is traditionally recognized for its anti-inflammatory and astringent capabilities, contributing to overall skin comfort and balance.
Research
Clinical Evidence
Medium confidenceN/A
Transparency
Dusting Analysis
While the Australian Industrial Chemicals Introduction Scheme (AICS) suggests concentrations of 0.2% or less in consumer products to minimize potential skin sensitization based on a Local Lymph Node Assay (LLNA EC3 22.3%) of the essential oil, a human repeat insult patch test (HRIPT) at 10% did not induce irritation or sensitization. This indicates a low risk for most individuals at typical cosmetic concentrations, with regulatory guidance often erring on the side of caution for broad consumer exposure.
The Formula
Formulation
Stability
The extract is highly susceptible to degradation when exposed to heat and light. A topical formulation initially stable at pH 6.90 showed color changes and a pH decrease to 5.79 after 90 days of storage at 45 °C, indicative of oxidation of active compounds like terpenes and flavonoids. Therefore, protection from both heat and light is crucial for maintaining its stability and efficacy.
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel has not specifically reviewed Schinus Terebinthifolia Fruit Extract. It is recognized by the FDA as a flavoring agent. The AICS assessed the essential oil, finding it to be of low acute toxicity, non-severely irritating to skin and eyes, and non-genotoxic. SkinSAFE identifies this ingredient as 'Irritant Free', further supporting its general compatibility, particularly when used at low concentrations in a single product.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Schinus Terebinthifolia Fruit Extract is a valuable ingredient, delivering effective antibacterial and antioxidant benefits with a generally low risk of irritation and sensitization at typical cosmetic concentrations, though robust formulation practices are essential to ensure its stability.
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