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Moumoujus

SCAEVOLA TACCADA LEAF EXTRACT.

Valuable / ANTIOXIDANT

Scaevola Taccada Leaf Extract is a botanical active renowned for its multifaceted skin benefits. It functions as a potent antioxidant, protecting skin from environmental aggressors, while also demonstrating significant anti-inflammatory and antimicrobial properties to promote healthier skin function.

Summary

Antioxidant Anti-inflammatory Antimicrobial Soothing Wound Healing

Science

Mechanism of Action

This extract operates on multiple biological pathways to support skin health. Its antioxidant power stems from neutralizing free radicals, which mitigates oxidative stress and cellular damage. Anti-inflammatory effects are achieved by actively reducing pro-inflammatory cytokines, such as IL-1β, and simultaneously enhancing beneficial anti-inflammatory cytokines like IL-10. This dual action helps to lessen tissue damage, cellular infiltration, and swelling. Furthermore, Scaevola Taccada Leaf Extract exhibits antimicrobial capabilities against bacteria like Staphylococcus aureus and Escherichia coli, contributing to its traditional use in skin repair and soothing various skin conditions.

Research

Clinical Evidence

Medium confidence
Effective range 1–2%
Optimal

2%

Key findings

  1. 01 Antioxidant efficacy was demonstrated *in vitro* with an EC50 of 476.7-643.8 µg/ml for the ethyl acetate fraction and 1134.43 µg/ml for the ethanol extract in DPPH scavenging assays.
  2. 02 In a mastitis mouse model, an internal dose of 400 mg/ml leaf extracts/g body weight significantly reduced pro-inflammatory cytokine IL-1β levels and mitigated tissue injury, cellular infiltration, and subcutaneous edema.
  3. 03 The extract was effective in boosting anti-inflammatory cytokine IL-10 levels in a *Staphylococcus aureus*-induced rat model.
  4. 04 Topical applications of 1% and 2% extracts showed weak to moderate inhibitory power against *Staphylococcus aureus* and *Escherichia coli*. Notably, a 2% methanol extract from old leaves produced a 7.00 mm inhibition zone against *S. aureus*.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Stability

No specific optimal pH range or stability notes are available. However, the presence of diverse bioactive compounds suggests that extraction using both polar (e.g., ethanol, methanol, water) and non-polar (e.g., ethyl acetate, chloroform) solvents is feasible, indicating a broad range of soluble components.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

No specific safety assessments by regulatory bodies such as CIR, SCCS, or FDA were found for Scaevola Taccada Leaf Extract.

Your Skin

Skin Compatibility

Yes Normal
No Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Scaevola Taccada Leaf Extract presents as a valuable multi-functional ingredient with documented antioxidant, anti-inflammatory, and antimicrobial properties, making it beneficial for various skin concerns despite limited comprehensive human clinical data.

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