Science
Mechanism of Action
This extract operates through multiple cellular pathways to optimize skin health. It functions as a powerful antioxidant by effectively scavenging free radicals and inhibiting oxygen-promoted reactions, thereby minimizing oxidative damage. Its anti-aging efficacy is driven by promoting collagen synthesis and secretion, reinforcing dermal structure, and enhancing elasticity, potentially through the activation of the TGF-β signaling pathway and suppression of collagen-degrading enzymes like MMP9. For skin brightening, it inhibits melanin production by downregulating MITF gene expression. Additionally, it acts as a skin conditioning emollient, improving dry skin and stabilizing the barrier by enhancing keratin barrier function (TGM1). The extract also exhibits anti-inflammatory properties by reducing reactive oxygen species and alleviating inflammatory aging, and supports skin regeneration and wound healing by stimulating keratinocyte and fibroblast proliferation and migration.
Research
Clinical Evidence
Medium confidence1.6%
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Maintains a shelf life of 1.5 to 1.8 years when stored correctly in a tightly sealed container, in a dry, cool, and well-ventilated environment.
Safety
Safety Profile
No skin irritation or anaphylaxis was reported during 50 routine clinical uses of a Saussurea involucrata skin-protecting cream. While not reviewed by the CIR, natural plant extracts are generally valued for their biocompatibility, and cosmetic ingredients within the EU undergo stringent safety assessments.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Saussurea Involucrata Callus Extract offers a valuable array of scientifically supported benefits, including potent antioxidant, anti-aging, moisturizing, and brightening effects, with a demonstrated low irritancy profile suitable for all skin types.
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References
Sources