SAURURUS CHINENSIS LEAF/ROOT EXTRACT.

This extract derives its efficacy from a rich profile of flavonoids and polyphenols, which confer significant antioxidant activity by neutralizing free radicals and reducing oxidative stress. Its anti-inflammatory capabilities are expressed through multiple pathways, including the blocking of inflammatory genes via the TAK1/AP-1 pathway, reduction of TNF-alpha synthesis by inhibiting the c-Raf-MEK1/2-ERK1/2 phosphorylation pathway, and suppression of nitrite production through upregulation of heme oxygenase-1. For complexion clarity, it helps balance skin's oil production, regulate excess sebum, and mitigate pore clogging. Furthermore, it combats uneven skin tone by inhibiting melanin production and decreasing alpha-MSH-induced tyrosinase and MITF expression, potentially through increased ERK activity, while also supporting skin hydration and barrier repair.