Get a Free 5ml Mini Now Free 5ml Mini With Every Order of The Mantle
Moumoujus

SAURURUS CHINENSIS FLOWER/LEAF/STEM EXTRACT.

Valuable / SKIN CONDITIONING

This botanical extract, derived from the flowers, leaves, and stems of Saururus chinensis, is a multi-functional ingredient known for its significant anti-inflammatory and antioxidant capabilities. It works to soothe irritated skin, protect against environmental aggressors, and promote a more even and balanced complexion. Additionally, it contributes to sebum regulation, making it beneficial for oily and sensitive skin types.

Summary

Anti-inflammatory Antioxidant Skin Brightening Sebum Regulating Skin conditioning Skin protecting Antimicrobial Astringent Emollient

Science

Mechanism of Action

Saururus Chinensis Flower/Leaf/Stem Extract exerts its benefits by modulating multiple cellular pathways. It significantly reduces inflammation by inhibiting key mediators such as tumor necrosis factor (TNF)-α and Interleukin-6 (IL-6) synthesis, and by blocking TAK1/AP-1 and c-Raf-MEK1/2-ERK1/2 phosphorylation. It also suppresses cyclooxygenase-2 (COX-2) and 5-lipoxygenase activities, and eotaxin expression. As a rich source of flavonoids and polyphenols, it functions as a potent antioxidant, neutralizing free radicals, safeguarding human keratinocytes from sun damage, and preventing the upregulation of matrix metalloproteinase (MMP-1) enzymes. Furthermore, the extract contributes to skin brightening by inhibiting melanin production, offers hydrating properties, and helps balance the skin's oil production by reducing excess sebum and mitigating pore clogging.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Dose-dependent inhibition of melanin production in B16F10 melanoma cells without inducing cytotoxicity, supporting its role in skin brightening.
  2. 02 Significant reduction in swelling, erythema, and serum levels of Interleukin-6 (IL-6), TNF-alpha, and collagen IgG in animal models of type II collagen-induced arthritis, indicating potent anti-inflammatory effects.
  3. 03 Inhibition of cyclooxygenase-2 (COX-2) dependent prostaglandin D2 generation (IC50 = 14.3 µg/ml) and leukotriene C4 production (IC50 = 0.3 µg/ml) in bone marrow-derived mast cells, highlighting its broad anti-inflammatory action.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

Saururus Chinensis Extract is generally regarded as safe for use in cosmetic formulations. However, as a natural botanical ingredient, individuals with sensitivities to plant extracts should consider performing a patch test prior to full application to identify any potential personal reactions such as localized irritation, redness, or itching. Currently, no specific safety assessments from the CIR, SCCS, or FDA have been published for SAURURUS CHINENSIS FLOWER/LEAF/STEM EXTRACT.

Your Skin

Skin Compatibility

Yes Normal
No Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Saururus Chinensis Flower/Leaf/Stem Extract is a valuable ingredient for precision skincare, offering scientifically supported anti-inflammatory, antioxidant, and skin-brightening benefits alongside sebum regulation and protective properties.

Related

Similar Ingredients

Finding similar ingredients…