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Moumoujus

SARGASSUM FULVELLUM EXTRACT.

Valuable CAS - / SKIN CONDITIONING

Sargassum Fulvellum Extract is a marine-derived active ingredient that offers comprehensive benefits to the skin. It exhibits potent antioxidant and anti-inflammatory properties, providing protection against environmental stressors and visibly reducing redness. The extract also deeply moisturizes and nourishes, contributing to enhanced skin elasticity and a radiant complexion.

Summary

Antioxidant Soothing Moisturizer/Humectant Anti-inflammatory Skin barrier repair Cell renewal Skin whitening

Science

Mechanism of Action

This extract operates through multiple biological pathways to support skin health. Its high antioxidant capacity neutralizes free radicals, mitigating premature skin aging. A rich blend of vitamins, minerals, and amino acids promotes skin hydration, nourishment, and elasticity, supporting cellular regeneration and toning. The extract fortifies the skin's natural barrier against external aggressors like pollution and UV damage. It actively calms irritated skin by inhibiting NF-κB activity and reducing the production of key inflammatory mediators and cytokines, including NO, TNF-α, IL-6, IL-1β, COX-2, and PGE2. Bioactive components such as sulfated polysaccharides (fucoidan), polyphenols (fucoxanthin, phlorotannins), and mycosporine-like amino acids collectively contribute to its antioxidant, anti-inflammatory, moisturizing, skin barrier repair, and potential skin brightening effects via tyrosinase inhibition. Furthermore, it boosts cell renewal and is highly hygroscopic, similar to the skin’s natural moisturizing factors.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Sargassum fulvellum water extract significantly inhibited IL-6 by over 50% in LPS-stimulated RAW 264.7 cells (in vitro). It also demonstrated dose-dependent inhibition of NO and TNF-α secretion and IL-1β expression.
  2. 02 Sargassum fulvellum ethanol extract administered orally reduced ear edema by 40% in mice.
  3. 03 Sargassum fulvellum ethanol extract effectively inhibited UVB-induced cytotoxicity and the production of pro-inflammatory proteins (COX-2, TNF-α, iNOS, PGE2, NO) in both in vitro human keratinocytes and in vivo BALB/c mice.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Safety

Safety Profile

CIR Status
Safe as used
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel has concluded that Sargassum Fulvellum Extract is safe for use in cosmetics under current practices. The FDA recognizes brown algae, including Sargassum species, as Generally Recognized As Safe (GRAS) for human consumption as flavor enhancers and adjuvants within good manufacturing practices. While generally well-tolerated, individuals with sensitivities to seafood should consider a patch test prior to widespread use.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

Sargassum Fulvellum Extract is a valuable, well-tolerated ingredient offering significant antioxidant, anti-inflammatory, and moisturizing benefits across all skin types.

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