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Moumoujus

SANTALUM ALBUM EXTRACT.

Valuable CAS 84787-70-2 / CLEANSING, SKIN CONDITIONING, SOOTHING

Santalum Album Extract, derived from the sandalwood tree, is a versatile botanical ingredient renowned for its comprehensive skin benefits. It delivers significant antioxidant protection, effectively calms inflammation, and supports deep skin hydration, making it suitable across a broad spectrum of skin concerns. This extract contributes to a balanced, radiant, and resilient complexion.

Summary

anti-inflammatory antioxidant antimicrobial moisturizing skin conditioning soothing anti-aging skin brightening astringent cleansing

Science

Mechanism of Action

The extract's anti-inflammatory properties are mediated by its ability to inhibit PDE enzymes and suppress the arachidonic acid pathway, specifically through alpha and beta santalol's inhibition of COX and LOX enzymes. It also activates 11β-HSD1 to regulate cortisol levels in keratinocytes and interferes with NF-κB activation. For its antimicrobial efficacy, it targets acne-causing bacteria, notably *Cutibacterium acnes*, and offers broad protection against fungi, yeast, and parasites. As a potent antioxidant, it neutralizes free radicals, thereby protecting skin from oxidative stress and premature aging. Moisturizing benefits stem from its capacity to hydrate, nourish, restore moisture levels, and reinforce the skin barrier. Alpha-santalol, a key constituent, also acts as a tyrosinase inhibitor, suggesting a role in reducing hyperpigmentation and promoting a more even skin tone. Furthermore, its astringent qualities assist in refining pores and managing excess oil production.

Research

Clinical Evidence

Medium confidence
Effective range 0.001–1%
Optimal

N/A

Key findings

  1. 01 An in vitro study demonstrated that an aqueous extract of sandalwood callus exhibited concentration-dependent antioxidant activity, achieving 48.7% DPPH scavenging and 53.2% hydroxyl radical scavenging at a 0.01% concentration (100 micrograms/ml).
  2. 02 Cosmetic compositions containing 'extract of depleted sandalwood' within a concentration range of 0.001%-1% are utilized for general skin, scalp, and appendage care, including the prevention of wrinkles and fine lines.

Transparency

Dusting Analysis

Not commonly dusted

No specific data provided to indicate this ingredient is commonly 'dusted' in cosmetic formulations for marketing purposes.

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
1%
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) has not specifically evaluated SANTALUM ALBUM EXTRACT. While a related ingredient, Santalum Album Oil, is generally considered safe and non-comedogenic/non-phototoxic at appropriate concentrations, specific data for the extract's use during pregnancy is not available. Although overall irritancy is low, a small percentage of individuals (0.1-2.4%) have reported allergic reactions to sandalwood oil; patch testing is recommended for all botanical ingredients due to individual variability.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

Santalum Album Extract is a valuable, multi-functional ingredient offering potent antioxidant, anti-inflammatory, and antimicrobial benefits suitable for all skin types, presenting a low risk of irritation or comedogenicity.

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References

Sources