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SANICULA EUROPAEA FLOWER/LEAF/STEM EXTRACT.

Valuable / SKIN CONDITIONING

Sanicula Europaea Flower/Leaf/Stem Extract is a botanical active, recognized for its diverse contributions to skin health. Composed of beneficial phenolic compounds, flavonoids, and tannins, this extract offers significant anti-inflammatory, wound-healing, and antimicrobial properties. It is a valuable ingredient for formulations aimed at soothing irritation, promoting dermal recovery, and providing astringent benefits.

Anti-inflammatory Antimicrobial Astringent Skin conditioning Wound healing

Science

This extract exerts its dermatological benefits through a synergistic action of its rich phytochemical profile, which includes phenolic compounds, tannins, flavonoids (such as quercetin and apigenin), and hydroxycinnamic acids (like rosmarinic and chlorogenic acids), alongside triterpenoid saponins. These constituents collectively impart hemostatic, antimicrobial, and astringent effects. Its anti-inflammatory activity is primarily mediated by inhibiting the formation of specific inflammatory mediators, thereby calming reactive skin states and supporting the natural healing cascade.


Research

Low confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Animal studies have indicated notable anti-inflammatory efficacy, observed at an internal concentration of 100 mg/kg in a formalin-induced paw oedema model.
  2. 02 Further animal research, utilizing aqueous and 70% ethanol extracts (1:10 raw material-to-solvent ratio), showcased accelerated wound healing by 4.84 to 5.34 days compared to the control group, and by 1.0 to 1.5 days relative to a reference drug. Additionally, bleeding time was significantly reduced by 48.29% to 49.56% compared to control groups.

Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Aqueous and hydroethanolic extracts are commonly employed in preparations, indicating good stability within these typical cosmetic solvent systems.


Safety

CIR Status
Not reviewed
Sensitization risk Low

While generally considered low-risk with moderate use, individuals with known sensitivities to the Apiaceae plant family should exercise caution due to the potential for allergic contact dermatitis. Patch testing is advised for susceptible individuals.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Valuable

This botanical extract demonstrates promising anti-inflammatory and wound-healing properties in animal studies, making it a valuable ingredient for targeted skin repair and soothing formulations, though human topical data is currently limited.


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