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SAMBUCUS WILLIAMSII PHYTOPLACENTA EXTRACT.

Valuable / ANTIMICROBIAL, ANTIOXIDANT, HAIR CONDITIONING, SKIN PROTECTING

Sambucus Williamsii Phytoplacenta Extract is a versatile botanical ingredient derived from the placenta of the *Sambucus williamsii* plant. This extract functions as a potent antioxidant, antimicrobial, and skin-protecting agent, actively working to diminish signs of aging and soothe irritated skin. It contributes to enhanced skin hydration and overall dermal health.

Summary

Antimicrobial Antioxidant Hair Conditioning Skin Protecting Anti-inflammatory Moisturizing Skin Brightening Anti-aging Collagen Boosting

Science

Mechanism of Action

This extract exerts its dermatological benefits through multiple mechanisms. Its rich flavonoid content provides robust antioxidant defense, safeguarding the skin from free radical damage and thereby reducing the appearance of fine lines and wrinkles. It exhibits anti-inflammatory properties that help to calm redness and irritation. Furthermore, it supports the skin's natural barrier function, aiding in moisture retention and preventing dehydration. The extract's antimicrobial action targets bacteria implicated in skin infections, offering specific benefits for acne-prone skin. It actively stimulates cellular proliferation, boosts collagen production, and inhibits collagenase (MMP-1) and elastase, enzymes critical for maintaining the extracellular matrix, which collectively improves skin elasticity and reduces wrinkle depth. It may also contribute to a more uniform skin tone by reducing dark spots.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

1%

Key findings

  1. 01 Studies indicate potent antibacterial activity against *P. gingivalis*, with concentrations around 1% (10 mg/mL) demonstrating optimal efficacy without cytotoxicity to human gingival fibroblasts. Higher concentrations (e.g., 4%) achieved full bactericidal effect but showed significant cytotoxicity.
  2. 02 Research shows promotion of collagen production and inhibition of matrix metalloproteinase-1 (MMP-1) and elastase activity, contributing to improved skin wrinkles.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

While specific optimal pH data for Sambucus Williamsii Phytoplacenta Extract is not extensively documented, related elderberry extracts (Sambucus nigra L.) have shown remarkable stability over extended periods (up to 180 days), particularly when formulated with appropriate solvents such as 45% ethanol.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

Specific safety evaluations by the Cosmetic Ingredient Review (CIR) or the Scientific Committee on Consumer Safety (SCCS) for Sambucus Williamsii Phytoplacenta Extract are currently unavailable. It is generally considered non-irritating for cosmetic application; however, there is a potential for irritation, inflammation, or dryness, especially when combined with other potentially problematic ingredients. It's important to note that the 'Generally Recognized As Safe' (GRAS) status granted by the FDA to elderberry (Sambucus nigra) extracts for food additives does not directly extend to this specific extract for cosmetic use.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Sambucus Williamsii Phytoplacenta Extract is a valuable multi-active ingredient offering significant antioxidant, antimicrobial, and anti-aging benefits, making it suitable for a broad range of skin types and concerns.

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