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Moumoujus

SALVIA MILTIORRHIZA ROOT EXTRACT.

Valuable CAS 90106-50-6 / SKIN CONDITIONING

Salvia Miltiorrhiza Root Extract is a multi-functional botanical ingredient recognized for its potent antioxidant and anti-inflammatory properties. It actively soothes skin, promotes cellular regeneration, and fortifies the skin's natural barrier, leading to a healthier and more radiant complexion.

Summary

Antioxidant Soothing Anti-inflammatory Skin Repair Barrier Support Microcirculation Enhancer

Science

Mechanism of Action

This extract functions as a powerful antioxidant, protecting the skin from environmental stressors through compounds like tanshinone IIA and rosmanol. It exhibits significant anti-inflammatory effects by inhibiting pro-inflammatory cytokines, reducing sensitivity, and modulating immune signaling pathways to alleviate allergic responses. Furthermore, it enhances microcirculation, stimulating skin regeneration, improving barrier function, and helping to balance natural oil production.

Research

Clinical Evidence

High confidence
Effective range 0.25–10%
Optimal

5%

Key findings

  1. 01 Topical applications ranging from 0.25% to 5% have demonstrated soothing effects, including the inhibition of PGE2 secretion and COX synthesis in damaged skin, reduction of redness, and strengthening of barrier function.
  2. 02 General usage levels between 5% and 10% are known to promote significant repair and regeneration of skin tissue, contributing to increased firmness and tenderness.
  3. 03 In vitro studies using 100 µg/mL significantly inhibited mast cell degranulation by 44.4% ± 1.6%, indicating potent anti-allergic effects.

Transparency

Dusting Analysis

Not commonly dusted

Effective concentrations for topical applications are well-defined, ranging from 0.25% to 10% for various skin benefits, indicating that it is not typically 'dusted' in formulations seeking demonstrable efficacy.

The Formula

Formulation

Solubility
Water
Optimal pH 4 – 6.5
0 7 14

Stability

The extract demonstrates good stability within a weak acidic pH environment, specifically between pH 4.0 and 6.5. While broadly water-soluble, it contains both hydrophilic phenolics and lipophilic tanshinones.

Conflicts

  • strong oxidizing agents

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Moderate

While generally regarded as having a 'well-documented safety profile', this ingredient is not an FDA-approved drug. The EWG Skin Deep database rates it as 'MODERATE' for Allergies & Immunotoxicity, citing evidence from the EU Cosmetics Directive. A significant concern is the recommendation for extracts to be free from cryptotanshinone, a component of the root associated with potential cardiotoxicity and developmental risks.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

Salvia Miltiorrhiza Root Extract is a valuable, multi-functional botanical celebrated for its potent antioxidant, anti-inflammatory, and skin-regenerative benefits across all skin types, though careful sourcing to exclude cryptotanshinone is essential.

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