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Moumoujus

SALACIA OBLONGA ROOT EXTRACT.

Insufficient Data / SKIN CONDITIONING

Salacia oblonga Root Extract is derived from a plant historically used in Ayurvedic medicine, known for its diverse bioactive compounds. While primarily studied for its oral metabolic benefits, this extract offers promising theoretical advantages for topical skin health, including antioxidant, anti-inflammatory, and antimicrobial properties.

Summary

Antioxidant Anti-inflammatory Antimicrobial

Science

Mechanism of Action

The proposed skin benefits of Salacia oblonga Root Extract are primarily attributed to compounds like mangiferin, a xanthonoid. Mangiferin functions as an antioxidant, actively combating oxidative stress and neutralizing free radicals. It also exhibits mild anti-inflammatory effects by inhibiting the release of inflammation mediators and shows broad-spectrum antimicrobial activity against various bacteria and fungi. Additionally, its antioxidant potential is linked to the inhibition of NADPH oxidase enzyme activity.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 No dedicated clinical studies on the topical application of Salacia oblonga Root Extract for skin benefits are available in the provided data. Oral intake studies indicate significant reductions in postprandial glucose (14-22%) and insulin (9-19%) responses in patients with type 2 diabetes following high-carbohydrate meals at doses of 240-480 mg. Furthermore, a 200 mg daily oral intake reported a 15% drop in fasting glucose over 6 weeks in subjects. These findings, however, pertain to internal metabolic regulation and do not directly demonstrate topical skin efficacy.

Transparency

Dusting Analysis

Not commonly dusted

Salacia oblonga is not commonly identified as an ingredient subject to 'dusting' in cosmetic formulations based on available data, primarily due to the lack of specific topical application studies and its main historical use as an oral supplement.

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Safety

Safety Profile

CIR Status
Not reviewed
Pregnancy
Caution
Sensitization risk Unknown

The Cosmetic Ingredient Review (CIR) has not assessed Salacia oblonga Root Extract for cosmetic use. While oral intake is considered possibly safe for short-term use, with single doses up to 1000 mg, potential side effects can include gastrointestinal discomfort such as gas, belching, abdominal pain, nausea, and diarrhea. Animal studies have indicated a good internal safety profile with a no observable adverse effect level (NOAEL) of 2,500 mg/kg/day in a 90-day oral feeding study in rats. However, specific topical safety data for cosmetic application, including maximum concentrations, irritancy, or sensitization potential, are currently unavailable. It is contraindicated during pregnancy and lactation due to insufficient safety data.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

Salacia oblonga Root Extract demonstrates theoretical promise for skin due to its antioxidant, anti-inflammatory, and antimicrobial properties; however, there is a distinct lack of dedicated clinical efficacy and safety data specifically for its topical application in skincare formulations.

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