Science
Mechanism of Action
This complex ingredient synergistically combines the benefits of Saccharomyces ferment filtrates and sericin. Saccharomyces ferments are rich in polysaccharides, peptides, vitamins, minerals, and amino acids, functioning as powerful natural antioxidants to neutralize free radicals and mitigate premature skin aging. They enhance natural moisturizing factors (NMFs) through amino acids and activate aquaporin 3 (AQP3), significantly improving skin hydration. Polysaccharides like β-glucan bolster the skin's protective barrier by stimulating tight junction protein synthesis. Furthermore, these ferments exhibit anti-inflammatory properties by down-regulating inflammatory cytokines and can inhibit elastase and tyrosinase activity, contributing to improved skin elasticity, tone, and reduced melanin generation. Sericin, extracted from silk glands, provides additional moisturizing, anti-wrinkle, and antioxidant capabilities, while sodium bicarbonate facilitates optimal pH regulation during the fermentation process.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 In a four-week study, continuous application of a Saccharomyces boulardii fermented product filtrate led to a 37.2% reduction in trans-epidermal water loss (TEWL) and a 62.5% increase in stratum corneum hydration.
- 02 A postbiotic extract derived from Saccharomyces cerevisiae fermentation demonstrated significant enzymatic inhibition, reducing elastase activity by 83.4% and tyrosinase activity by 42.4%. It also stimulated cytokeratin 14 production, vital for skin structure.
- 03 The aforementioned Saccharomyces cerevisiae postbiotic extract exhibited notable anti-inflammatory activity at this concentration.
- 04 A formulation incorporating Saccharomyces cerevisiae fermentation residue was shown to enhance skin whitening by decreasing tyrosinase activity and suppressing melanin synthesis.
Transparency
Dusting Analysis
Clinical studies demonstrate efficacy at percentages as low as 1% for anti-inflammatory effects and 5% for hydration and barrier improvement, indicating it is an active ingredient utilized for its functional benefits rather than for superficial marketing claims.
The Formula
Formulation
Synergies
- The combination of Saccharomyces ferments and sericin provides enhanced moisturizing, antioxidant, and barrier-strengthening effects.
Safety
Safety Profile
The CIR Expert Panel noted 'Insufficient Data' for a broad group of yeast-derived ingredients, requesting additional dermal sensitization data. However, Saccharomyces Ferment Filtrate, a key component, is generally considered safe for cosmetic use with a low incidence of allergic reactions or irritation. The FDA affirms Saccharomyces cerevisiae as 'Generally Recognized As Safe' (GRAS) for food use. Patch testing is advisable for individuals with particularly sensitive skin.
Your Skin
Skin Compatibility
Our Assessment
Verdict
This multi-beneficial ferment filtrate offers significant hydrating, barrier-strengthening, antioxidant, and skin tone-improving properties, making it a valuable active ingredient for a wide range of skincare formulations.
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