Science
Mechanism of Action
This fermented ingredient functions as a powerful antioxidant by actively neutralizing free radicals, thereby protecting the skin from oxidative damage and premature aging. It acts as a natural humectant, efficiently drawing and retaining moisture within the skin to significantly improve hydration, refine texture, and enhance overall appearance. Its anti-aging efficacy is attributed to stimulating collagen production, which subsequently improves skin elasticity and firmness, visibly reduces fine lines and wrinkles, and contributes to protection against UV radiation. The ferment's inherent anti-inflammatory properties contribute to soothing and calming irritated skin. Additionally, it exhibits skin brightening capabilities by promoting an even skin tone and reducing the appearance of dark spots and hyperpigmentation. It supplies essential nutrients including amino acids, beta-glucan, and vitamins, supporting skin cell regeneration, nourishing the skin, strengthening its protective barrier against environmental stressors, and aiding in maintaining a balanced natural skin microbiome.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 Clinical observations of related Saccharomyces Ferment Filtrate, when applied in concentrations of 0.1%-5% for leave-on products or up to 10% for rinse-off formulations, indicate improvements in overall skin health and appearance. Specific benefits noted include reduced inflammation, promotion of collagen production, enhanced skin elasticity, improved texture, and a reduction in the appearance of fine lines and wrinkles. It also contributes to strengthened skin barrier function and enhanced moisturization.
- 02 A formulation containing 0.01% (v/v) of Saccharomyces cerevisiae fermentation residue (a related material) demonstrated increased skin whitening activity in a clinical study. This effect was linked to its radical scavenging activity and attenuation of tyrosinase activity, which significantly suppressed melanin generation.
- 03 Saccharomyces/Selenium Ferment itself has been recognized for its potent antioxidant properties, significant moisturizing benefits, anti-aging effects via collagen stimulation and UV protection, soothing anti-inflammatory action, and skin brightening capabilities through evening skin tone and reducing hyperpigmentation.
Transparency
Dusting Analysis
This ingredient, particularly in powdered forms, is identified as a respiratory sensitizer and hazardous through inhalation. Consequently, stringent safety precautions and controlled environments are imperative during manufacturing and handling to effectively mitigate worker exposure.
The Formula
Formulation
Stability
Optimal stability for this ingredient is indicated within a slightly acidic pH range of 4.0 to 5.0. This is supported by data on related Saccharomyces Cerevisiae Extract, which exhibits stability within this range, and the pH adjusted for selenium solution during Saccharomyces cerevisiae fermentation (pH 5.0).
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel has concluded that many yeast-derived ingredients, including those from Saccharomyces cerevisiae, are safe for cosmetic use under current practices. However, Saccharomyces/Selenium Ferment itself carries a 'safe with restrictions' status, largely due to occupational handling concerns. While related 'selenised yeast Saccharomyces cerevisiae' has been assessed by EFSA as not being a skin sensitizer, skin irritant, or eye irritant, it is classified as a respiratory sensitizer and hazardous through inhalation for workers. The FDA recognizes and defines selenium-enriched yeast for food applications. Despite this, EWG Skin Deep rates Saccharomyces/Selenium Ferment with 'high use restrictions' and deems it 'unacceptable' for EWG VERIFIED products, citing concerns such as low-moderate non-reproductive organ system toxicity and moderate occupational hazards. This suggests that while dermal contact typically presents a low irritancy risk, caution is advised regarding inhalation exposure and use in high concentrations.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Saccharomyces/Selenium Ferment is a valuable, multi-functional ingredient that delivers significant antioxidant, anti-aging, moisturizing, and skin brightening benefits across all skin types, with careful consideration for handling protocols during manufacturing.
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References
Sources